CC BY-NC-ND 4.0 · The Arab Journal of Interventional Radiology 2018; 02(03): S12
DOI: 10.1055/s-0041-1730679
Abstract

Role of Computed Tomography-Guided Percutaneous Celiac Plexus Neurolysis in Relieving Pain Due to Abdominal Malignancy

Hesham Mohamed Atef Soliman
National Liver Institute-Menoufia University, Shebin El-kom, Egypt
,
Elsayed Elmekawy Elsayed
Faculty of medicine-Menoufia University, Shebin El-kom, Egypt
,
Mohamed Shawky Elwarraky
National Liver Institute-Menoufia University, Shebin El-kom, Egypt
,
Tarek Fawzy Abd Ella
Faculty of medicine-Menoufia University, Shebin El-kom, Egypt
› Author Affiliations

Background: Cancer-related pain remains a common problem in oncologic practice and has major influence on patient's comfort, tolerance of therapies, and probably survival This study aims to assess the efficacy of Computed tomography (CT)-guided celiac plexus neurolysis (CPN) to relieve pain in patients with advanced abdominal cancer. Methods: CT-guided CPN through anterior technique was done for 20 adult patients (their ages ranges between 30 and 70 years) suffering from abdominal cancer pain using ethanol (90%) as a neurolytic agent. To assess the degree of pain relief, the visual analog score (VAS) was used to assess the degree of pain; immediately after injection, 1 week, 1 month, and 3 months' post-CPN procedure. Results: Marked decrease of the pain intensity in all the patients was noted as a sharp fall of the VAS score immediately after injection of the neurolytic agent and more pronounced in the 1st day post-CPN with the relatively stationary course for 3 months. The VAS score base line was 9.1 ± 0.85. One day after CPN, pain severity decreased markedly to 1.3 ± 0.71, 1 week later, the decrease in pain severity almost maintained at the same level 1.7 ± 0.89, 1 month after CPN, the decrease in pain severity also maintained at the same level 1.9 ± 0.79 and 3 months after CPN pain severity still decreased significantly to 2.3 ± 1.02. The decline in the severity of pain at its average before and at different sequences after CPN recorded high significant statistical difference P < 0.001. Conclusion: CT-guided CPN is an effective and safe method for relieving severe pain due to abdominal cancer.



Publication History

Article published online:
11 May 2021

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