Acute Myeloid Leukemia Presenting with an unusual Phenotype

SHARMILA GHOSH; GK SHIVA; SHAILA SHINDE; Y BADRINATH; SUBODH DHOND; HEMANI JAIN; PRATIBHA AAMRE

doi:10.1055/s-0041-1733111

Indian Journal of Medical and Paediatric Oncology, Table of Contents

CC BY-NC-ND 4.0 · Indian J Med Paediatr Oncol 2005; 26(01): 53-57
DOI: 10.1055/s-0041-1733111

Case Report

Acute Myeloid Leukemia Presenting with an unusual Phenotype

SHARMILA GHOSH

Dept.of Medical Oncology,Tata Memorial Hospital,Mumbai-400012,India

,

GK SHIVA

Dept.of Medical Oncology,Tata Memorial Hospital,Mumbai-400012,India

,

SHAILA SHINDE

Dept.of Medical Oncology,Tata Memorial Hospital,Mumbai-400012,India

,

Y BADRINATH

Dept.of Medical Oncology,Tata Memorial Hospital,Mumbai-400012,India

,

SUBODH DHOND

Dept.of Medical Oncology,Tata Memorial Hospital,Mumbai-400012,India

,

HEMANI JAIN

Dept.of Medical Oncology,Tata Memorial Hospital,Mumbai-400012,India

,

PRATIBHA AAMRE

Dept.of Medical Oncology,Tata Memorial Hospital,Mumbai-400012,India

› Author Affiliations

References
1 Weinstein, H. J. Acute Myeloid Leukemia. In Childhood Leukemias (UK 1999), edited by C. H. Pui, C. H., Cambridge University Press.
2 Behm, F.G., Campana, D. Immunophenotyping. In Childhood Leukemias (UK 1999), edited by Pui, C. H. Cambridge university press.
3 Specchia, G. , Mestice, A. , Storlazzi, T.C. , Anelli, L. , Pannunzio, A. , Roberti, M. G. , Rocchi, M. , Liso, V. A novel translocation t(2;9)(q14; p12) in AML-M2 with an uncommon phenotype: myeloperoxidase-positive and myeloid antigen negative. Leukemia Research, 2001;25:501-507.
4 Buccheri, V. , Shetty, V. , Yoshida, N. , Morilla, R. , Matutes, E. , Catovsky, D. The role of an antimyeloperoxidase antibody in the diagnosis and classification of acute leukemias: a comparison with light and electron microscopy. British Journal of Haematology, 1992;80:63-68.
5 Khalil, S. H. , Jackson, J. M. , Qari, M. H. , Pyle, H. Acute myeloblastic leukemia (AML-M2) expressing CD19 B-cell lymphoid antigen without myeloid surface antigens. Letter to the editors. Leukemia Research, 18,145.
6 Seshi, B. , Kashyap, A. , Bennett, J. M. Acute myeloid leukemia with an unusual phenotype: meloperoxidase (+), CD13 (-), CD14 (-) and CD33 (-). British Journal of Haematology, 1992;81:374-377.
7 Arber DA, Glackin C, Lowe G, Medeiros LJ, Slovak ML. Presence of t(8;21)(q22;q22) in myeloperoxidase-positive myeloid surface antigen negative acute myeloid leukemia. Am J Clin Patho, 1997;107:68-73.
8 Hirai K, Torimoto Y, Moriichi K, Sato K, et. al Discordant expression of myeloid antigens and Myeloperoxidase in a case of t(8;21) positive AML expressing CD7. Int J Hematol, 1999;70:30-35.
9 Garcia VJA, Martin M, Delgado I, et. al Acute myeloid leukemia M2 and t(8;21)(q22;q22) with an unusual phenotype: myeloperoxidase(+), CD 13(-), CD14(-), CD33(-). Ann Hematol , 1999;78(5):237-240.
10 Kraguljac N, Marisavljevic D, Jankovic G, Characterisation of CD13 and CD33 surface antigennegative acute myeloid leukemia. Am J Clin Pathol, 2000;114:29-34.
11 Khalidi, H. S. ,Medeiros, L. L. , Chang, K. L., The immunophenotype of adult acute myeloid leukemia: high frequency of lymphoid antigen expression and comparison of immunophenotype, French- American- British classification and karyotypic abnormalities. American Journal of Clinical Pathology, 1998;109(2):211-220.
12 Oliviera, M. S. P. , Matutes, E. , Rani, S. , Morilla, R. , Catovsky, D. Early expression of MCS2 (CD13) in the cytoplasm of blast cells from acute myeloid leukemia. Acta Haematologica, 1988;80:61-64.
13 Head, D. R. , Pui, C. H. Diagnosis and classification. In Childhood Leukemias (UK 1999), edited by Pui, C. H. Cambridge University Press. 1999.
14 Mitelman, F. Catalog of Chromosome Aberrations in Cancer, 4th edn,. Wiley and Liss, New York Publication. 1995