CC BY-NC-ND 4.0 · Indian J Radiol Imaging 2021; 31(03): 670-677
DOI: 10.1055/s-0041-1735505
Pictorial Essay

Hepatobiliary and Gastrointestinal Involvement in Langerhans Cell Histiocytosis—Spectrum of Three Cases

1   Department of Radiology, VPS Lakeshore Hospital, Kochi, Kerala, India
,
Muhammed Jasim Abdul Jalal
2   Department of Internal Medicine and Rheumatology, VPS Lakeshore Hospital, Kochi, Kerala, India
,
3   Department of Pathology, VPS Lakeshore Hospital, Kochi, Kerala, India
,
Anupama Gopalakrishnabhakthan
4   Department of Medical Oncology, VPS Lakeshore Hospital, Kochi, Kerala, India
,
1   Department of Radiology, VPS Lakeshore Hospital, Kochi, Kerala, India
› Author Affiliations
Funding None.

Abstract

Langerhans cell histiocytosis (LCH) is a rare group of disorder, due to clonal neoplastic proliferation of dendritic cells in the bone marrow expressing a Langerhans cell phenotype.[1] This disease particularly affects the pediatric age group and young adults and often presents with skin rashes, lung infiltrates, and bone lesions. It can also manifest with endocrine dysfunction and hematopoietic disorders. Involvement of gastrointestinal tract is very rare. Herein, we present a spectrum of three cases with gastrointestinal involvement.

Financial Disclosure

None.




Publication History

Article published online:
07 September 2021

© 2021. Indian Radiological Association. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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