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DOI: 10.1055/s-0041-1740592
Epidemiological Profile of 96 Intracranial Tumors Treated in a Single Reference Center
Perfil epidemiológico de 96 tumores intracranianos tratados em um único centro de referência
Abstract
Objectives The present study aims to categorize the prevalence of intracranial tumors surgically treated at the neurosurgery service of Hospital Universitário Evangélico Mackenzie (HUEM) between 2016 and 2018.
Material and Methods This survey included patients surgically treated due to primary or metastatic intracranial neoplasia between 2016 and 2018 at a referral center in the city of Curitiba. These patients were analyzed for epidemiological, histopathological, and topographic data, and they underwent an assessment of the outcome at the time of hospital discharge.
Results A total of 96 patients met the inclusion criteria. The most prevalent tumor was the glioma, with 39.6% of the sample, with glioblastoma being the most prevalent histological type. Brain metastases and meningiomas represented, respectively, 21.9% and 18.8% of the total. There was a predominance of supratentorial and intra-axial tumors in our sample.
Conclusion Glioma was the most commonly found tumor, directly associated with high morbidity and mortality. The development of new and more effective drugs with action directed at the molecular level of intracranial tumors may be the path to a longer survival and improvement in the quality of life of these patients.
Resumo
Objetivos O presente estudo tem como objetivo levantar a prevalência dos tumores intracranianos abordados cirurgicamente pelo Serviço de Neurocirurgia do Hospital Universitário Evangélico Mackenzie (HUEM) entre 2016 e 2018.
Material e Métodos Foram selecionados pacientes com diagnóstico de neoplasia intracraniana primária ou metastática no intervalo de 2016 a 2018 tratados cirurgicamente em um centro de referência na cidade de Curitiba. Esses pacientes foram analisados quanto a dados epidemiológicos, histopatológicos, e topográficos e foram ainda submetidos a uma avaliação do desfecho no momento da alta hospitalar.
Resultados O total de 96 pacientes preencheram os critérios de inclusão. O tumor mais prevalente foi o glioma, com 39,6% da amostra, sendo o glioblastoma o tipo histológico mais prevalente. As metástases cerebrais e os meningiomas representaram, respectivamente, 21,9% e 18,8% do total de pacientes. Houve um predomínio de tumores supratentotoriais e intra-axiais em nossa amostra.
Conclusão O glioma foi o tumor mais encontrado, associado à elevada morbimortalidade. O desenvolvimento de fármacos novos e mais efetivos com ação direcionada ao nível molecular dos tumores intracranianos pode ser o caminho para uma maior sobrevida e melhora da qualidade de vida desses pacientes.
Publikationsverlauf
Eingereicht: 14. Dezember 2020
Angenommen: 16. April 2016
Artikel online veröffentlicht:
20. Dezember 2021
© 2021. Sociedade Brasileira de Neurocirurgia. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commecial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)
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