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CC BY-NC-ND 4.0 · Int Arch Otorhinolaryngol 2022; 26(01): e148-e151
DOI: 10.1055/s-0041-1740987
Original Research
Special Article COVID-19

ENT Manifestations in Patients Suffering from COVID-19: Study from a COVID Hospital in North India

Anitya Srivastava 
1   Department of ENT, Dr. Ram Manohar Lohia Institute of Medical Sciences, Lucknow, Uttar Pradesh, India
,
Ashish Chandra Agarwal 
1   Department of ENT, Dr. Ram Manohar Lohia Institute of Medical Sciences, Lucknow, Uttar Pradesh, India
,
Syed Zeeshan Alam 
1   Department of ENT, Dr. Ram Manohar Lohia Institute of Medical Sciences, Lucknow, Uttar Pradesh, India
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Abstract

Introduction COVID-19 has been one of the worst pandemics faced by the human civilization, and otorhinolaryngological manifestations are commonly seen in this disease.

Objective The present study was done to profile the ear, nose, and throat (ENT) manifestations in patients diagnosed with COVID-19. An attempt has also been made to assess whether there was any difference between the symptoms of different strains of COVID-19. A brief review of the current knowledge of the transmission of the disease and its treatment has also been done.

Methods A cross-sectional, record-based study was conducted in a COVID hospital of India between May and July 2020. Descriptive statistics were used and appropriate parametric/nonparametric tests were applied to assess the association between various variables.

Results Out of 250 patients, 80 cases were asymptomatic and 170 were symptomatic. Most of the symptomatic patients had sore throat and nasal congestion.

Conclusion Knowledge of the ENT manifestations of COVID-19 is essential for its early identification and to devise appropriate prevention protocols for the benefit of health care workers (HCWs) and of the general population.

Keywords

covid-19 - ENT - otorhinolaryngology manifestations - pandemic - SARS-COV-2

Ethical Standards

The authors assert that all the procedures contributing to the present work comply with the ethical standards of the relevant national and institutional guidelines on human experimentation and with the Helsinki Declaration of 1975, as revised in 2008.


Financial Support

The present research received no specific grant from any funding agency, commercial or not-for-profit sectors.




Publication History

Received: 17 May 2021

Accepted: 17 October 2021

Article published online:
25 January 2022

© 2022. Fundação Otorrinolaringologia. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commecial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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  • References

  • 1 Guo YR, Cao QD, Hong ZS. et al. The origin, transmission and clinical therapies on coronavirus disease 2019 (COVID-19) outbreak - an update on the status. Mil Med Res 2020; 7 (01) 11-13
    CrossrefPubMedGoogle Scholar
  • 2 Wu F, Zhao S, Yu B. et al. A new coronavirus associated with human respiratory disease in China. Nature 2020; 579 (7798): 265-269
    CrossrefPubMedGoogle Scholar
  • 3 WHO. 2020. Novel Coronavirus – China. Geneva: WHO;
    Google Scholar
  • 4 Li Q, Guan X, Wu P. et al. Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus-Infected Pneumonia. N Engl J Med 2020; 382 (13) 1199-1207
    CrossrefPubMedGoogle Scholar
  • 5 Young BE, Ong SWX, Kalimuddin S. et al; Singapore 2019 Novel Coronavirus Outbreak Research Team. Epidemiologic Features and Clinical Course of Patients Infected With SARS-CoV-2 in Singapore. JAMA 2020; 323 (15) 1488-1494
    CrossrefPubMedGoogle Scholar
  • 6 Chen N, Zhou M, Dong X. et al. Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study. Lancet 2020; 395 (10223): 507-513
    CrossrefPubMedGoogle Scholar
  • 7 Dagur HS, Dhakar S. Genome Organization of Covid-19 and Emerging Severe Acute Respiratory Syndrome Covid-19 Outbreak: A Pandemic. EJMO 2020; 4 (02) 107-115
    Google Scholar
  • 8 Lu R, Zhao X, Li J. et al. Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding. Lancet 2020; 395 (10224): 565-574
    CrossrefPubMedGoogle Scholar
  • 9 Krajewska J, Krajewski W, Zub K, Zatoński T. COVID-19 in otolaryngologist practice: a review of current knowledge. Eur Arch Otorhinolaryngol 2020; 277 (07) 1885-1897
    CrossrefPubMedGoogle Scholar
  • 10 Sah R, Rodriguez-Morales AJ, Jha R. et al. Complete Genome Sequence of a 2019 Novel Coronavirus (SARS-CoV-2) Strain Isolated in Nepal. Microbiol Resour Announc 2020; 9 (11) e00169-e20
    PubMedGoogle Scholar
  • 11 Zhang T, Wu Q, Zhang Z. Probable Pangolin Origin of SARS-CoV-2 Associated with the COVID-19 Outbreak. Curr Biol 2020; 30 (07) 1346-1351.e2
    CrossrefPubMedGoogle Scholar
  • 12 WHO. current stats on COVID 19 infection. 2020 [Accessed 31 st July,2020]. Geneva
    PubMedGoogle Scholar
  • 13 COVID-19: infection prevention and control (IPC) [Internet]. GOV.UK. 2020. Available from: https://www.gov.uk/government/publications/wuhan-novel-coronavirus-infection-prevention-and- van Doremalen N, Bushmaker T, Morris DH, et al. Aerosol and Surface Stability of SARS-CoV-2 as Compared with SARS-CoV-1. N Engl J Med 2020; 382 (16) 1564-1567
    CrossrefPubMedGoogle Scholar
  • 14 Van Doremalen N, Bushmaker T, Morris DH. et al. Aerosol and surface stability of SARS-CoV-2 as compared with SARS-CoV-1. N Engl J Med 2020; 382 (16) 1564-1567
    CrossrefPubMedGoogle Scholar
  • 15 Guan WJ, Ni ZY, Hu Y. et al; China Medical Treatment Expert Group for Covid-19. Clinical Characteristics of Coronavirus Disease 2019 in China. N Engl J Med 2020; 382 (18) 1708-1720
    CrossrefPubMedGoogle Scholar
  • 16 Mahase E. Covid-19: WHO declares pandemic because of “alarming levels” of spread, severity, and inaction. BMJ 2020; 368: m1036
    CrossrefPubMedGoogle Scholar
  • 17 Lescure FX, Bouadma L, Nguyen D. et al. Clinical and virological data of the first cases of COVID-19 in Europe: a case series. Lancet Infect Dis 2020; 20 (06) 697-706
    CrossrefPubMedGoogle Scholar
  • 18 Mohfw.gov.in.2020. Mohf/Home. [online]. [Accessed 5 july 2020] at: https://www.mohfw.gov.in/index.html
    Google Scholar
  • 19 European Rhinologic Society. (2020). [Internet]. 2020 Available from: https://www.researchgate.net/publication/340848609_Nasal_Pharyngeal_and_Laryngeal_Endoscopy_Procedures_during_COVID19_Pandemic_Available_Recommendations_from_National_and_International_Societies
    Google Scholar
  • 20 Chan JYK, Wong EWY, Lam W. Practical Aspects of Otolaryngologic Clinical Services During the 2019 Novel Coronavirus Epidemic: An Experience in Hong Kong. JAMA Otolaryngol Head Neck Surg 2020; 146 (06) 519-520 DOI: 10.1001/jamaoto.2020.0488.
    CrossrefPubMedGoogle Scholar
  • 21 Wang D, Hu B, Hu C. et al. Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China. JAMA 2020; 323 (11) 1061-1069
    CrossrefPubMedGoogle Scholar
  • 22 Zhu N, Zhang D, Wang W. et al; China Novel Coronavirus Investigating and Research Team. A Novel Coronavirus from Patients with Pneumonia in China, 2019. N Engl J Med 2020; 382 (08) 727-733
    CrossrefPubMedGoogle Scholar
  • 23 Gautret P, Lagier JC, Parola P. et al. Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial. Int J Antimicrob Agents 2020; 56 (01) 105949
    CrossrefPubMedGoogle Scholar
  • 24 WHO. current stats on COVID 19 infection. 2020 [Accessed 6th July,2020]. Geneva.
    PubMedGoogle Scholar
  • 25 Hopkins C, Surda P, Whitehead E, Kumar BN. Early recovery following new onset anosmia during the COVID-19 pandemic - an observational cohort study. J Otolaryngol Head Neck Surg 2020; 49 (01) 26
    CrossrefPubMedGoogle Scholar
  • 26 Berton AM, Prencipe N, Giordano R, Ghigo E, Grottoli S. Systemic steroids in patients with COVID-19: pros and contras, an endocrinological point of view. J Endocrinol Invest 2021; 44 (04) 873-875
    CrossrefPubMedGoogle Scholar
  • 27 Singh AK, Majumdar S, Singh R, Misra A. Role of corticosteroid in the management of COVID-19: A systemic review and a Clinician's perspective. Diabetes Metab Syndr 2020; 14 (05) 971-978 DOI: 10.1016/j.dsx.2020.06.
    CrossrefGoogle Scholar
  • 28 Fadel R, Morrison AR, Vahia A. et al; Henry Ford COVID-19 Management Task Force. Early Short-Course Corticosteroids in Hospitalized Patients With COVID-19. Clin Infect Dis 2020; 71 (16) 2114-2120
    CrossrefPubMedGoogle Scholar
  • 29 Wu X, Cai Y, Huang X. et al. Co-infection with SARS-CoV-2 and Influenza A Virus in Patient with Pneumonia, China. Emerg Infect Dis 2020; 26 (06) 1324-1326
    CrossrefPubMedGoogle Scholar