Download PDF
CC BY-NC-ND 4.0 · International Journal of Recent Surgical and Medical Sciences 2023; 09(01): 056-058
DOI: 10.1055/s-0041-1741561
Case Report

A Rare Case of Isolated Agenesis of the Thyroid Isthmus: Surgical Implications

Gaurang Singhal 
1   Department of ENT, Atal Bihari Vajpayee Institute of Medical Sciences, Dr. Ram Manohar Lohia Hospital, Delhi, India
,
Pradeepti Nayak 
1   Department of ENT, Atal Bihari Vajpayee Institute of Medical Sciences, Dr. Ram Manohar Lohia Hospital, Delhi, India
,
Nishi Sharma
1   Department of ENT, Atal Bihari Vajpayee Institute of Medical Sciences, Dr. Ram Manohar Lohia Hospital, Delhi, India
› Author Affiliations Funding None.
› Further Information
   Permissions and Reprints

Abstract

The thyroid gland is the largest endocrine gland in the body and pathologies related to this gland are a fairly common occurrence in clinical practice. Various developmental abnormalities can distort the morphology of the thyroid gland. Variations in anatomy may have critical clinical implications, both in terms of manifestations and surgical complications. In this report, we discuss a rare case of isolated agenesis of the thyroid isthmus that was discovered incidentally during the right thyroid lobectomy of a female patient who was diagnosed as the case of colloid goiter.

Keywords

agenesis - isthmus - thyroid


Publication History

Article published online:
07 February 2022

© 2022. Medical and Surgical Update Society. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

Thieme Medical and Scientific Publishers Pvt. Ltd.
A-12, 2nd Floor, Sector 2, Noida-201301 UP, India

 

  • References

  • 1 Jain A, Pathak S. Rare developmental abnormalities of thyroid gland, especially multiple ectopia: a review and our experience. Indian J Nucl Med 2010; 25 (04) 143-146
    CrossrefPubMedGoogle Scholar
  • 2 Sankar KD, Bhanu PS, Susan PJ, Gajendra K. Agenesis of isthmus of thyroid gland with levator glandulae thyoidea. Int J Anat Var 2009; 2: 29-30
    Google Scholar
  • 3 Pastor VJ, Gil VJ, De Paz Fernandez FJ, Cachorro MB. Agenesis of the thyroid isthmus. Eur J Anat 2006; 10: 83-84
    Google Scholar
  • 4 Melnick JC, Stemkowski PE. Thyroid hemiagenesis (hockey stick sign): a review of the world literature and a report of four cases. J Clin Endocrinol Metab 1981; 52 (02) 247-251
    CrossrefPubMedGoogle Scholar
  • 5 Kumar A, Banarjee A, Harikrishan V. Case report: a congenital anomaly of thyroid gland with agenesis of isthmus and presence of pyramidal lobe. J Evol Med Dent Sci 2013; 2: 7899-7903
    CrossrefGoogle Scholar
  • 6 Marshall CF. Variations in the form of the thyroid gland in man. J Anat Physiol 1895; 29 (Pt 2): 234-239
    PubMedGoogle Scholar
  • 7 De Felice M, Di Lauro R. Thyroid development and its disorders: genetics and molecular mechanisms. Endocr Rev 2004; 25 (05) 722-746
    CrossrefPubMedGoogle Scholar
  • 8 Vassart G, Dumont JE. Thyroid dysgenesis: multigenic or epigenetic ... or both?. Endocrinology 2005; 146 (12) 5035-5037
    CrossrefPubMedGoogle Scholar
  • 9 Gangbo E, Lacombe D, Alberti EM, Taine L, Saura R, Carles D. Trisomy 22 with thyroid isthmus agenesis and absent gall bladder. Genet Couns 2004; 15 (03) 311-315
    PubMedGoogle Scholar
  • 10 Ozkan OF, Asık M, Toman H, Ozkul F, Cıkman O, Karaayvaz M. Agenesis of isthmus of the thyroid gland in a patient with graves-basedow disease and a solitary nodule. Case Rep Surg 2013; 2013: 608481 DOI: 10.1155/2013/608481.
    CrossrefPubMedGoogle Scholar