Drug Res (Stuttg) 2017; 67(03): 183-188
DOI: 10.1055/s-0042-122007
Original Article
© Georg Thieme Verlag KG Stuttgart · New York

A Study of Acute Poisoning Cases Admitted to the University Hospital Emergency Department in Tabriz, Iran

Mehdi Oraie
1   Clinical Laboratory Science, Azad University of Medical Sciences, Tabriz, Iran
,
Mir-Jamal Hosseini
2   Department of Pharmacology and Toxicology, School of Pharmacy, Zanjan University of Medical Sciences, Zanjan, Iran
3   Zanjan Applied Pharmacology Research Center, Zanjan University of Medical Sciences, Zanjan, Iran
,
Mina Islambulchilar
2   Department of Pharmacology and Toxicology, School of Pharmacy, Zanjan University of Medical Sciences, Zanjan, Iran
,
Seyed-Hasan Hosseini
4   Department of Management, Faculty of Administrative Sciences and Economics, University of Isfahan, Isfahan, Iran
,
Mehdi Ahadi-Barzoki
5   Department of clinical pharmacy, school of pharmacy, Zanjan University of Medical Sciences, Zanjan, Iran
,
Habib Sadr
6   Fajr Psychiatry Hospital, Tabriz, Iran
,
Hashem Yaghoubi
7   Department of Biology, Ardabil Branch, Islamic Azad University, Ardabil, Iran
› Author Affiliations
Further Information

Publication History

received 07 June 2016

accepted 21 November 2016

Publication Date:
10 January 2017 (online)

Abstract

Chemical substances have an important threat due to extensive use in medicine, agriculture, industry and environment. In this retrospective study, etiological and demographic characteristics of acute poisoning cases admitted to a hospital in Iran were investigated. We compared these data with those reported from other parts of the country and the international experiences to evaluate any difference if exists. 7 052 poisoned cases admitted to the hospital from April 2006 to March 2013, by data collected from the medical record in poison center section. According to our results there is a predominance of male patients and the majority of the poisoned patients were between 20–30 years old. Drug poisoning was the most common cause of poisonings. The most frequently involved drugs were benzodiazepines and antidepressants. The seasonal distribution of our study showed a peak in summer. To prevent acute poisonings, the social education about the risk assessment of central nervous system-acting drugs and reduction of the exposure period of people to pesticides are recommended. This study suggested a proper educational program for the public and primary care units. Our results provide useful information for preventive strategies.

 
  • References

  • 1 Sobhani AR, Shojaii-Tehrani H, Nikpour E et al. Drug and chemical poisoning in Northern Iran. Arch Iran Med 2000; 3: 88-91
  • 2 Gould MS, Kramer RA. Youth suicide prevention. Suicide Life Threat Behav 2001; 31: 6-31
  • 3 Dianat S, Zarei M-R, Hassanian-Moghaddam H et al. Tricyclic antidepressants intoxication in Tehran, Iran: Epidemiology and associated factors. Hum Exp Toxicol 2010; 30: 283-288
  • 4 Islambulchilar M, Islambulchilar Z, Kargar-Maher MH. Acute adult poisoning cases admitted to a university hospital in Tabriz, Iran. Hum Exp Toxicol 2009; 28: 185-190
  • 5 Litovitz TL, Klein-Schwardz W, Caravati EM et al. Annual report of the American Association Of Poison Control Centers Toxic Exposure Surveillance System. Am J Emerg Med 1999; 17: 435-487
  • 6 Mehrpour O, Abdollahi M. Poison treatment centers in Iran. Hum Exp Toxicol 2012; 31: 303-304
  • 7 Kristinsson J, Palsson R, Gudjonsdottr GA et al. Acute poisonings in Iceland: a prospective nationwide study. Clin Toxicol (Phila) 2008; 46: 126-132
  • 8 Baydin A, Yardan T, Aygun D et al. Retrospective evaluation of emergency service patients with poisoning: a 3-year study. Adv Ther 2005; 22: 650-658
  • 9 Sorodoc V, Jaba IM, Lionte C et al. Epidmiology of acute poisoning in a tertiary from Iasi County, Romania. Hum Exp Toxicol 2011; 30: 1896-1903 Exp Toxicol 2006; 25: 217–223
  • 10 Mert E, Gamsiz Bilgin N. Demographical, etiological and clinical characteristics of poisonings in Mersin, Turkey. Hum
  • 11 Ahmadi A, Pakravan N, Ghazizadeh Z. Pattern of acute food, drug, and chemical poisoning in Sari City, Northern Iran. Hum Exp Toxicol 2010; 29: 731-738
  • 12 Fernando R. The National Poisons Information Centre in Sri Lanka: the first ten years. J Toxicol Clin Toxicol 2002; 40: 551-555
  • 13 Akhlaghi M, Arbabi Z, Khadivi R. Pattern of acute poisoning in Shahrekord (Western Iran). Asian J Epidemiol 2009; 2: 9-12
  • 14 Thomas SH, Bevan L, Bhattacharyya S et al Presentation of poisoned patients to accident and emergency departments in the north of England. Hum Exp Toxicol 1996; 15: 466-470
  • 15 Ramesha KN, Rao KB, Kumar GS. Pattern and outcome of acute poisoning cases in a tertiary care hospital in Karnataka, India. Indian J Crit Care Med 2009; 13: 152-155
  • 16 Abdollahi M, Jalali N, Sabzevari O et al. A retrospective study of poisoning in Tehran. J Toxicol Clin Toxicol 1997; 35: 387-393
  • 17 Reith DM, Pitt WR, Hockey R. Childhood poisoning in Queensland: an analysis of presentation and admission rates. J Paediatr Child Health 2001; 37: 446-450
  • 18 Tufekci IB, Curgunlu A, Sirin F. Characteristics of acute adult poisoning cases admitted to a university hospital in Istanbul. Hum Exp Toxicol 2004; 23: 347-351
  • 19 Bronstein AC, Spyker DA, Cantilena Jr LR et al. Annual report of the American Association of Poison Control Centers’ National Poison Data System (NPDS): 26th Annual report. Clin Toxicol 2008; 47: 911-1084
  • 20 Unverir P, Atilla R, Karcioglu O et al. A retrospective analysis of antidepressant poisonings in the emergency department: 11-year experience. Hum Exp Toxicol 2006; 25: 605-612
  • 21 Kiyotaka K, Matsumoto Y, Tomooko J et al. Acute drug poisoning at Critical Care Departments in Japan. J Clin Hosp Pharm 1998; 24: 340-348
  • 22 Karbakhsh M, Salehian Zandi N. Acute opiate overdose in Tehran: the forgotten role of opium. Addict Behav 2007; 32: 1835-1842
  • 23 Izadi-Mood N, Gheshlaghi F, Sharafi SE. Fatal poisoning cases admitted to the Emergency Department of poisoning, Noor Hospital, Isfahan, Iran. J Legal Med 2003; 9: 122-126
  • 24 Habibisaravi R, Navaeinia S, Farnia S et al. Alcohol, cannabinoids, and opioids abuse and dependence among psychiatric inpatients. Iran J Psychiatry Behav Sci 2015; 9: 229-232
  • 25 Shadnia S, Esmaily H, Sasanian G et al. Pattern of acute poisoning in Tehran-Iran in 2003. Hum Exp Toxicol 2007; 26: 753-756
  • 26 Mortazavi SM, Haaji Y, Khonche A et al. Epidemiology and causes of poisoning in patients referred to loqman hospital, Tehran, Iran during summer 2010. IJT 2010; 6: 642-648
  • 27 Ku CH, Hung HM, Leong WC et al. Outcome of patients with carbon monoxide poisoning at a far-east poison center. PLoS One 2015; 10: e0118995
  • 28 Rahimi R, Nikfar S, Abdollahi M. Increased morbidity and mortality in acute human organophosphate-poisoned patients treated by oximes: meta-analysis of clinical trials. Hum Exp Toxicol 2006; 25: 157-162