Endoscopy 2017; 49(02): 191-198
DOI: 10.1055/s-0042-122140
Position statement
© Georg Thieme Verlag KG Stuttgart · New York

Endoscopic management of Barrett’s esophagus: European Society of Gastrointestinal Endoscopy (ESGE) Position Statement

Bas Weusten
1  Department of Gastroenterology and Hepatology, St. Antonius Hospital, Nieuwegein, The Netherlands
2  Department of Gastroenterology and Hepatology, Academic Medical Center, Amsterdam, The Netherlands
,
Raf Bisschops
3  Department of Gastroenterology, University Hospital Leuven, Leuven, Belgium
,
Emanuel Coron
4  Institut des Maladies de l’Appareil Digestif, CHU and University, Nantes, France
,
Mário Dinis-Ribeiro
5  Department of Gastroenterology, Portuguese Oncology Institute-Porto, Porto, Portugal
,
Jean-Marc Dumonceau
6  Gedyt Endoscopy Center, Buenos Aires, Argentina
,
José-Miguel Esteban
7  Department of Endoscopy, Hospital Clinico San Carlos, Madrid, Spain
,
Cesare Hassan
8  Department of Gastroenterology, Nuovo Regina Margherita Hospital, Rome, Italy
,
Oliver Pech
9  Department of Gastroenterology and Interventional Endoscopy, St. John of God Hospital, Regensburg, Germany
,
Alessandro Repici
10  Department of Gastroenterology, Humanitas Research Hospital, Humanitas University, Milano, Italy
,
Jacques Bergman
2  Department of Gastroenterology and Hepatology, Academic Medical Center, Amsterdam, The Netherlands
,
Massimiliano di Pietro
11  MRC Cancer Unit, University of Cambridge, Cambridge, United Kingdom
› Author Affiliations
Further Information

Publication History

Publication Date:
25 January 2017 (online)

Abstract

Current practices for the management of Barrett’s esophagus (BE) vary across Europe, as several national European guidelines exist. This Position Statement from the European Society of Gastrointestinal Endoscopy (ESGE) is an attempt to homogenize recommendations and, hence, patient management according to the best scientific evidence and other considerations (e.g. health policy). A Working Group developed consensus statements, using the existing national guidelines as a starting point and considering new evidence in the literature. The Position Statement wishes to contribute to a more cost-effective approach to the care of patients with BE by reducing the number of surveillance endoscopies for patients with a low risk of malignant progression and centralizing care in expert centers for those with high progression rates.

Main statements

MS1 The diagnosis of BE is made if the distal esophagus is lined with columnar epithelium with a minimum length of 1 cm (tongues or circular) containing specialized intestinal metaplasia at histopathological examination.

MS2 The ESGE recommends varying surveillance intervals for different BE lengths. For patients with an irregular Z-line/columnar-lined esophagus of < 1 cm, no routine biopsies or endoscopic surveillance is advised. For BE ≥ 1 cm and < 3 cm, BE surveillance should be repeated every 5 years. For BE ≥ 3 cm and < 10 cm, the interval for endoscopic surveillance should be 3 years. Patients with BE with a maximum extent ≥ 10 cm should be referred to a BE expert center for surveillance endoscopies. Patients with limited life expectancy and advanced age should be discharged from endoscopic surveillance.

MS3 The diagnosis of any degree of dysplasia (including “indefinite for dysplasia”) in BE requires confirmation by an expert gastrointestinal pathologist.

MS4 Patients with visible lesions in BE diagnosed as dysplasia or early cancer should be referred to a BE expert center. All visible abnormalities, regardless of the degree of dysplasia, should be removed by means of endoscopic resection techniques in order to obtain optimal histopathological staging

MS5 All patients with a BE ≥ 10 cm, a confirmed diagnosis of low grade dysplasia, high grade dysplasia (HGD), or early cancer should be referred to a BE expert center for surveillance and/or treatment. BE expert centers should meet the following criteria: annual case load of ≥10 new patients undergoing endoscopic treatment for HGD or early carcinoma per BE expert endoscopist; endoscopic and histological care provided by endoscopists and pathologists who have followed additional training; at least 30 supervised endoscopic resection and 30 endoscopic ablation procedures to acquire competence in technical skills, management pathways, and complications; multidisciplinary meetings with gastroenterologists, surgeons, oncologists, and pathologists to discuss patients with Barrett’s neoplasia; access to experienced esophageal surgery; and all BE patients registered prospectively in a database.

Appendix e1 – e4