Abstract
Astroblastoma is an uncommon neuroepithelial primary brain neoplasm with speculative
histopathological origin and unpredictable clinical behavior. They can be easily misdiagnosed,
as they are rarely encountered in clinical practice and share common radiological
and histopathologic appearances with other glial neoplasms. Herein, we report a case
of high-grade astroblastoma in a 27-year-old female with complaints of seizures and
loss of consciousness, which was misdiagnosed as atypical meningioma on neuroimaging,
due to its rarity and superficial cortical location appearing as extra-axial mass.
Although intraoperative findings were also of an extra-axial tumor, the histology
and immunophenotype was of an astroblastoma; thus, highlighting the role of histopathology
and immunohistochemistry.
Keywords
astroblastoma - histology - neuroepithelial brain tumor
