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CC BY-NC-ND 4.0 · South Asian J Cancer 2022; 11(03): 183-189
DOI: 10.1055/s-0042-1743420
Original Article
Breast Cancer

Quality of Life Post Breast Cancer Surgery: Comparison of Breast Conservation Surgery versus Modified Radical Mastectomy in a Developing Country

Kurian Cherian
1   Department of Surgical Oncology, Regional Cancer Centre, Thiruvananthapuram, Kerala, India
,
Nitish Rajan Acharya
1   Department of Surgical Oncology, Regional Cancer Centre, Thiruvananthapuram, Kerala, India
,
Rexeena V. Bhargavan
1   Department of Surgical Oncology, Regional Cancer Centre, Thiruvananthapuram, Kerala, India
,
Paul Augustine 
1   Department of Surgical Oncology, Regional Cancer Centre, Thiruvananthapuram, Kerala, India
,
Jagathnath K.M. Krishnan 
1   Department of Surgical Oncology, Regional Cancer Centre, Thiruvananthapuram, Kerala, India
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Abstract

Introduction Breast cancer survivors are the largest group of female cancer survivors. Oncologic breast surgery can have a profound impact on a woman's body image and sense of self that can significantly affect their quality of life (QOL). The paucity of data about the effect of type of surgery on QOL of Indian breast cancer survivors has led to this study.

Materials and Methods This prospective study included consecutive female early breast cancer patients who underwent primary surgery, that is, breast conservation surgery (BCS) or modified radical mastectomy (MRM) from January 1, 2015 to December 31, 2015. The primary objective was the comparison of QOL using European Organization for the Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30) and EORTC QLQ-BR 23 between the two groups at 6 months and 1 year postsurgery with the baseline.

Results One hundred and thirty-eight patients were included of which 62 underwent BCS and 76 underwent MRM. BCS patients fared better with respect to physical functioning, dyspnea, fatigue, appetite loss, and body image at 6 months (p < 0.05) as compared with MRM. At 1 year postsurgery, BCS patients fared better with respect to physical functioning, role functioning, global health status, body image, sexual enjoyment, and dyspnea, while MRM patients fared better in emotional functioning and future prospectives (p < 0.05).

Conclusion Patients undergoing BCS have a better QOL with respect to various functional and symptom scales at 6 months and 1 year. However, patients undergoing MRM perform better in terms of future perspective and emotional functioning at 1 year.

Keywords

breast cancer - breast conservation surgery - modified radical mastectomy - quality of life

Sources

Nil.


Note

Presented as a poster in the annual meeting of the Association of Radiation Oncologists of India in September 2017.




Publication History

Article published online:
25 April 2022

© 2022. MedIntel Services Pvt Ltd. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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