A Rare Case of Multicentric Primary Pulmonary Artery Sarcoma: Eliminating the Masquerade with Multimodality Imaging

Abstract

A 68-year-old male presented with a short history of exertional dyspnea and a provisional diagnosis of pulmonary thromboembolism was made. However, chest radiograph and further investigations in the form of computed tomography pulmonary angiogram, magnetic resonance imaging of thorax, and whole body fluorodeoxyglucose (FDG) positron emission tomography-computed tomography revealed a large mass arising from the distal left pulmonary artery extending into adjacent lung and another lesion near the root of the main pulmonary artery, both of which showed post-contrast enhancement and intense FDG uptake. Tissue sampling by transthoracic computed tomography-guided biopsy and immunohistochemistry confirmed the diagnosis of pulmonary artery angiosarcoma. Here, we present such a case of very rare occurrence which, in view of multicentricity and substantial extension into adjacent lung, is the first of its kind to be reported, to the best of our knowledge.

Keywords

pulmonary artery sarcoma - sarcoma - angiosarcoma - wall eclipsing sign - PAS

Ethical Approval and Consents

This report describes a rare diagnosis from routine diagnostic procedures. Hence, approval from the institutional review board was not obtained. Written informed consents for all the procedures were obtained before they were performed. For this type of study, consent for publication is not required as the data to be published is sufficiently anonymized.

Publication History

Article published online:
29 May 2022

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