Subscribe to RSS
DOI: 10.1055/s-0042-1744766
IMPACT OF DOUBLE-PIGTAIL PLASTIC STENTS IN THE ADVERSE EVENT RATE OF PANCREATIC FLUID COLLECTIONS, GALLBLADDER DRAINAGES AND CHOLEDOCHAL DRAINAGES USING LUMEN-APPOSING METAL STENTS
Aims Regarding lumen apposing metal stents (LAMS), the benefit of coaxial double pigtail stents remains unclear. We aimed at assessing their effect on the adverse events (AEs) rate in pancreatic collections, gallbladder and choledochal drainages.
Methods We performed a subanalysis of the the RNPAL case series, which retrieved all transmural LAMS between January 2019 and January 2020 in 31 centres, including all technically successful LAMS placed in pancreatic collections, EUS-guided gallbladder drainage (EUS-GBD) and common bile duct drains (EUS-CBDD). AEs were identified though centralised periodic follow-up until withdrawal, death, or up to 1 year, using standardized telephone questionnaires. We used the log-rank test to evaluate the effect of double-pigtail stents and Cox regression techniques for other possible risk factors.
Results We included 140 pancreatic collections (67.9% WONs, 32.1% pseudocysts), 79 EUS-GBD and 49 EUS-CBDD. [Table 1] shows their baseline characteristics. Double-pigtail stents were used in 46.4-55.7% of cases, according to the procedure. We identified 46 AE (11 severe/fatal) in pancreatic collections, 10 in EUS-GBD (4 severe/fatal) and 13 in EUS-CDS (3 severe/fatal). The log-rank test documented a risk reduction with double-pigtail stents in pancreatic collections ( p=0.02) and in EUS-GBD ([Figure 1], p=0.04). We did not observe differences in EUS-CDS (p=0.57). The only risk factor identified was the presence of biliopancreatic tumors in gallbladder drainages (HR 5.2 (95% CI: 1.2-21.8), p=0.03).
Pancreatic fluid collections (n=140) |
Gallbladder drainages (n=79) |
Choledochal drainages (n=49) |
|
---|---|---|---|
Sex male n (%) |
107 (76.4%) |
42 (53.2%) |
24 (49%) |
Age (med, IRC) |
62.9 (50.8–71.2) |
84.5 (76.5–90.1) |
81.2 (69.3–85.6) |
Neoplasm, n (%) |
5 (3.6%) |
17 (21.5%) |
46 (93.9%) |
Pig-tail, n (%) |
65 (46.4%) |
44 (55.7%) |
25 (51%) |
Conclusions Double-pigtail stents might reduce the AE risk in pancreatic collections and gallbladder drainages.
Publication History
Article published online:
14 April 2022
© 2022. European Society of Gastrointestinal Endoscopy. All rights reserved.
Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany