PLACE OF A SYSTEMATIC UPPER GASTROINTESTINAL ENDOSCOPY IN CROHN'S DISEASE

Aims Esophagogastroduodenoscopy (EGD) with the realization of biopsies, in Crohn's disease (CD), researchs upper locations of the disease. Our study aimed to study the interest of systematic EGD with anatomopathological study in the detection of upper CD locations.

Methods A retrospective study was conducted involving all patients with CD followed in our center over a period of 4 years (January 2016- January 2020).

Results 56 patients with CD were included in this study, of which 53.6% were female. The mean age was 33.29 years. In our series, Only 19.23% (n=5) of the EGDs were normal. The most frequent endoscopic abnormalities found were: fundic gastropathy that was congestive in 26.92% of cases (n=7) and nodular in 7.69% (n=2); congestive antropathy in 46.15% (n=12) and nodular in 15.38% (n=4); ulcerated or congestive bulbitis in 7.69% (n=2) and 19.23% (n=5) , respectively. Duodenitis was observed in 11.53% of patients (n=3). Anatomopathological examination, noted chronic active gastritis in 66.7% of patients who have had systematic EGD, vs 92.9% in symptomatic patients, without statistically significant difference (p=0.11), the same for presence of granuloma (16.7% in the 1st group vs 14.3% in the 2nd group, p=0.64), and the presence of a duodenal lymphocytic infiltrate (8.3% vs 0%, p=0,46).

Conclusions According to our study, a systematic EGD, in CD, has an important contribution in the detection of the upper localizations which constitute a severity factor of the disease.

Publication History

Article published online:
14 April 2022