LONG TERM OUTCOME OF GASTROINTESTINAL ENDOSCOPIC RESECTION IN PATIENTS WITH LIVER CIRRHOSIS

Aims Endoscopic resection has developed over the years. The main complications are perforation and bleeding. This study aimed to evaluate safety and effectiveness of digestive endoscopic resection in patients with cirrhosis

Methods This retrospective, open-label, single-center study included all consecutive patients with cirrhosis who were admitted for endoscopic resection between 2004 and 2020. Safety, efficacy, and risk factors for delayed bleeding were analyzed.

Results A total of 8970 patients underwent endoscopic resection for gastrointestinal neoplasia, and 228 had cirrhosis. Although the risk of post procedure bleeding is high in Child B patients (Child A – 3/231, 1.29%, Child B 4/41, 9.75%), the procedure can be performed relatively safely. After the procedure, there was one case of death due to bleeding, and the other cases were due to cirrhosis or liver cancer.

Conclusions Endoscopic resection was safe and effective in patients with mild (Child – Pugh class A/B) cirrhosis, and should be proposed as a first option for treatment of superficial neoplasia. Additional data in patients with severe cirrhosis are needed to confirm the safety in this population.

Publication History

Article published online:
14 April 2022