Homeopathy 2023; 112(02): 107-109
DOI: 10.1055/s-0042-1749147
Original Research Article

Homeopathic Products as a Complementary Dietary Additive for Pigs in their Growing and Finishing Phases

Geraldyne Nunes Wendt
1   Animal Science Department, State University of Western Paraná, Marechal Cândido Rondon, Brazil
,
2   Animal Science Department, Federal University of Viçosa, Viçosa, Brazil
,
Liliana Bury de Azevedo
1   Animal Science Department, State University of Western Paraná, Marechal Cândido Rondon, Brazil
,
Paulo Evaristo Rupolo
1   Animal Science Department, State University of Western Paraná, Marechal Cândido Rondon, Brazil
,
Cristine Regina Gregory
1   Animal Science Department, State University of Western Paraná, Marechal Cândido Rondon, Brazil
,
Josiane Aparecida Volpato
1   Animal Science Department, State University of Western Paraná, Marechal Cândido Rondon, Brazil
,
Silvana Teixeira Carvalho
1   Animal Science Department, State University of Western Paraná, Marechal Cândido Rondon, Brazil
,
Paulo Levi de Oliveira Carvalho
1   Animal Science Department, State University of Western Paraná, Marechal Cândido Rondon, Brazil
,
Tiago Junior Pasquetti
3   Animal Science Department, State University of Mato Grosso do Sul, Aquidauana, Brazil
› Institutsangaben

Abstract

Background Homeopathic products (HP) have been proposed for the prevention of disease and as a complementary dietary additive in pig farming, with resulting improved performance and quality of life of the animals and with benefits for food safety. The aim of this study was to assess the addition of HP to pig feed and its effects on growth performance, dietary protein utilization, nutrient digestibility, meat quality, and economic feasibility.

Methods A total of 80 male pigs, body weight 32.8±2.3kg, were allocated in a randomized design, with two treatments of 10 replications and four animals per experimental unit. Treatments were composed of a control diet (CD) or CD+HP (Finalvitaplus+Figotonus, 1.1kg/ton feed of each product). The outcome measures used were growth performance (body weight gain) and feed efficiency (body weight gain per unit of feed consumed), efficiency of dietary protein utilization (blood urea nitrogen), nutrient digestibility (apparent digestibility coefficient and apparent nutrient digestibility), meat quality (including pH, temperature, color, liquid loss by cooking and thawing, intramuscular fat and meat tenderness), and economic feasibility (cost of the diets).

Results There was no effect (p >0.05) of treatments on growth performance of the pigs, though the group that received HP showed an 8.93% greater feed efficiency than the control group (p=0.077). The animals in the control group had a 14.37% higher blood urea nitrogen concentration in the finishing I phase (70–100kg body weight) compared with those fed HP (p=0.028), indicating lower protein utilization in the controls. There was comparative improvement in digestibility coefficient and in nutrient digestibility in pigs fed HP in the growing–finishing phase (p <0.05). There was no differential effect of treatments on meat quality or economic feasibility (p >0.05).

Conclusion The addition of HP to the diet of growing–finishing pigs produced some improvement in their dietary protein utilization, nutrient digestibility and feed efficiency, though it did not affect their growth performance, meat quality or economic feasibility.



Publikationsverlauf

Eingereicht: 21. September 2021

Angenommen: 21. Februar 2022

Artikel online veröffentlicht:
02. September 2022

© 2022. Faculty of Homeopathy. This article is published by Thieme.

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany

 
  • References

  • 1 Maes DGD, Dewulf J, Piñeiro C, Edwards S, Kyriazakis I. A critical reflection on intensive pork production with an emphasis on animal health and welfare. J Anim Sci 2020; 98: S15-S26
  • 2 Brum JS, Konradt G, Bazzi T. et al. Características e frequência das doenças de suínos na Região Central do Rio Grande do Sul. Pesqui Vet Bras 2013; 33: 1208-1214
  • 3 Puls CL, Hammer JM, Eggers K. et al. Effects of two feeding periods of tiamulin fed in combination with chlortetracycline for control and treatment of swine respiratory and enteric disease and subsequent growth performance of growing-finishing pigs. Transl Anim Sci 2018; 3: 113-122
  • 4 Filippitzi ME, Brinch Kruse A, Postma M. et al. Review of transmission routes of 24 infectious diseases preventable by biosecurity measures and comparison of the implementation of these measures in pig herds in six European countries. Transbound Emerg Dis 2018; 65: 381-398
  • 5 Apley MD, Bush EJ, Morrison RB, Singer RS, Snelson H. Use estimates of in-feed antimicrobials in swine production in the United States. Foodborne Pathog Dis 2012; 9: 272-279
  • 6 Holtkamp D, Rotto H, Garcia R. The economic cost of major health challenges in large U.S. swine production systems. Paper presented at: Proceedings of American Association of Swine Veterinary Conference; 2007: 85-89
  • 7 Luning P, Kirezieva K, Hagelaar G, Rovira J, Uyttendaele M, Jacxsens L. Performance assessment of food safety management systems in animal-based food companies in view of their context characteristics: a European study. Food Control 2015; 49: 11-22
  • 8 Noschang JP, De Moraes RE, Carpinelli NA. et al. Promotores de crescimento (antibióticos) na alimentação de suínos – Revisão de Literatura REDVET. Rev Electrón Vet 2017; 18: 1-12
  • 9 Costa NC, Araújo RL, Freitas GBL. Homeopatia: Um campo terapêutico fundamental no cuidado veterinário de animais de produção. Rev Salus 2009; 3: 75-89
  • 10 Munshi R, Talele G, Shah R. In-vitro evaluation of antimicrobial activities of Escherichia coli, Klebsiella pneumoniae, Salmonella typhi, Neisseria gonorrhoeae, and Candida albicans nosodes. Homeopathy 2022; 111: 42-48
  • 11 Yalgi VS, Bhat KG. Evaluation of anti-inflammatory properties of homoeopathic gel preparations of Calendula officinalis, Arnica montana, Echinacea angustifolia and Hypericum perforatum by zymography—an in vitro study. Int J Hum Sci 2020; 4: 38-42
  • 12 Vargas DP, Nörnberg JL, Mello RO, Sheibler RB, Milani MP, Mello FCB. Correlações entre contagem bacteriana total e parâmetros de qualidade do leite. Rev Bras Cienc Vet 2014; 20: 241-247
  • 13 Costa Filho LCC, Queiroz VLD, Souza MFDA, Zúccari CESN, Costa EV. Homeopatia aplicada à reprodução animal. Arq Ciênc Vet Zool 2014; 17: 63-68
  • 14 Camerlink I, Ellinger L, Bakker EJ, Lantinga EA. Homeopathy as replacement to antibiotics in the case of Escherichia coli diarrhoea in neonatal piglets. Homeopathy 2010; 99: 57-62
  • 15 da Silva ICM, Bremm B, Teixeira JL. et al. Spatialization of Brazilian pig production: relationship between productive, physical, environmental, and socio-economic variables. Trop Anim Health Prod 2017; 49: 951-958
  • 16 Nunes R, Lima LF, Rocha RMP, Oliveira L, Campello CC, Figueiredo JR. Utilização do cultivo in vitro de folículos pré-antrais suínos inclusos em tecido ovariano (in situ) como modelo de avaliação da eficiência de medicamentos homeopáticos na foliculogênese inicial. Cienc Anim Bras 2018; 19: 1-8
  • 17 Soto FRM, Vuaden ER, Coelho CP. et al. Reproductive performance of sows inseminated with diluted semen treated with homeopathic medicine. Int J High Dilution Res 2010; 9: 51-57
  • 18 Soto FRM, Vuaden ER, Coelho Cd, Benites NR, Bonamin LV, de Azevedo SS. A randomized controlled trial of homeopathic treatment of weaned piglets in a commercial swine herd. Homeopathy 2008; 97: 202-205
  • 19 Felippelli G, Valente PP. Utilização de medicamentos homeopáticos incorporados à ração de leitões e avaliação da incidência de afecções do 7° ao 28° dia de idade. Nucl Anim 2009; 1: 79-95
  • 20 Kiefer C, Rizzardi R, Oliveira BF, Silva CM, Martins LP, Fantini CC. Homeopathic complex in the prevention and treatment of diarrhea in suckling piglets. Rev Bras Saúde Prod Anim 2012; 13: 74-82
  • 21 Coelho CP, Soto FRM, Vuaden ER, Melville PA, Oliveira FCS, Benites NR. Evaluation of preventive homeopathic treatment against Colibacillosis in swine production. Int J High Dilution Res 2009; 8: 183-190
  • 22 Coelho CP, Soto FRM, Vuaden ER. et al. Escherichia coli infected swine with identification of virulence factors involved. J High Dilution Res 2014; 13: 197-206
  • 23 Santos FR, Santana RO, Carvalho EA, Costa NA, Minafra CS, Oliveira PR. Desempenho e perfil sérico bioquímico de frangos de corte alimentados com rações contendo produtos homeopáticos. Rev Bras Saúde Prod Anim 2014; 15: 394-405
  • 24 Ribeiro JS, Gonçalves TM, Campos FR, Faria WL, Machado Neto OR. Homeopatia na terminação de novilhos nelores e tabapuãs confinados. Agropecuária Científica no Semi-Árido 2011; 7: 38-44
  • 25 Mazón-Suástegui JM, García-Bernal M, Saucedo PE, Campa-Córdova Á, Abasolo-Pacheco F. Homeopathy outperforms antibiotics treatment in juvenile scallop Argopecten ventricosus: effects on growth, survival, and immune response. Homeopathy 2017; 106: 18-26
  • 26 Filippsen LF, Moletta JL, Minho AP. et al. Aconitum napellus no pré-abate e seu efeito na qualidade da carne bovina. Rev Ciênc Agrovet 2011; ed. especial, art. n° 84
  • 27 Fuzzinato MM, Andretto AP, Braccini GL, Alves MM, Visentainer JV, Vargas L. Effect of a homeopathic product HomeoAqua Mega 3® on performance and lipid profile of the Nile tilapia head (Oreochromis niloticus). Cienc Anim Bras 2019; 20: 1-10
  • 28 Lebret B, Čandek-Potokar M. Review: pork quality attributes from farm to fork. Part I. Carcass and fresh meat. Animal 2022; 16 (Suppl 1): 100402
  • 29 Reig M, Aristoy MC, Toldrá F. Variability in the contents of pork meat nutrients and how it may affect food composition databases. Food Chem 2013; 140: 478-482
  • 30 Andriguetto JM, Perly L, Minardi I. et al. Nutrição animal: as bases e os fundamentos da nutrição animal os alimentos. 2nd ed. São Paulo: Nobel; 2002
  • 31 Real CM. Ficha técnica da Homeosuis Finalvitaplus®. Real H Nutrição e Saúde Animal; 2017
  • 32 Real CM. Ficha técnica da Homeobase Figotonus®. Real H Nutrição e Saúde Animal, 2017
  • 33 Rostagno HS, Albino LFT, Hannas MI. et al. Tabelas Brasileiras para Aves e Suínos. Composição de Alimentos e Exigências Nutricionais. 2nd ed. Viçosa, MG: UFV, Departamento de Zootecnia; 2017
  • 34 Moreno AM, Sobestiansky J, Lopez AC, Sobestiansky AAB. Colheita e processamento de amostras de sangue em suínos para fins de diagnóstico. Concórdia, MG: EMBRAPA-CNPSA; 1997. . Documentos 41
  • 35 Sakomura NK, Rostagno HS. Métodos de pesquisa em nutrição de monogástricos. 2nd ed. Jaboticabal: Funep; 2016
  • 36 Kavanagh S, Lynch PB, Mara OF, Cafrey PJ. A comparison of total collection and marker technique for the measurement of apparent digestibility of diets for growing pigs. Anim Feed Sci Technol 2001; 89: 49-58
  • 37 Silva DJ, Queiroz AC. Análise de alimentos: métodos químicos e biológicos. 3rd ed. Viçosa, MG Editora: UFV; 2002
  • 38 Van Keulen J, Young BA. Evaluation of acid-insoluble ash as natural marker in ruminant digestibility studies. J Anim Sci 1977; 44: 282-287
  • 39 Sakomura NK, Rostagno HS. Métodos de pesquisa em nutrição de monogástricos. 1st ed. Jaboticabal: Funep; 2007
  • 40 Brazil. Ministério da Agricultura, Pecuária e Abastecimento. Instrução normativa n.3°. Brasília-DF; 2000
  • 41 Bridi AM, Silva CA. Avaliação da carne suína. 1st ed. Londrina: Midiograf; 2009
  • 42 NPPC, National Pork Producers Council. Pork Composition Quality Assessment Procedures. 1st ed. Des Moines: EP Berg; 2000
  • 43 Ramos EM, Gomide LAM. Avaliação da qualidade de carnes: Fundamentos e metodologias. 2nd ed. Viçosa: UFV; 2017
  • 44 Kauffman RG, Eikelenboom G, van der Wal PG, Merkus G, Zaar M. The use of filter paper to estimate drip loss of porcine musculature. Meat Sci 1986; 18: 191-200
  • 45 Bellaver C, Fialho ET, Prota JFS, Gomes PC. Radícula de malte na alimentação de suínos em crescimento e terminação. Pesqui Agropecu Bras 1985; 20: 969-974
  • 46 Gomes MFM, Barbosa HP, Fialho ET, Ferreira AS, Lima GJMM. Análise econômica da utilização de triguilho para suínos. Concórdia: EMBRAPA-CNPSA; 1991. :1–2 (Comunicado Técnico, 179)
  • 47 SAS® University Edition – Statistical Analyses System – SAS/University Edition, © 25 SAS Institute Inc.
  • 48 Cuprum TR. Arte Méd Ampl. 2017; 37: 12-18
  • 49 Konratha EL, Neves BM, Lunardi PS. et al. Investigation of the in vitro and ex vivo acetylcholinesterase and antioxidant activities of traditionally used Lycopodium species from South America on alkaloid extracts. J Ethnopharmacol 2012; 139: 58-67
  • 50 Gülçin İ, Elias R, Gepdiremen A, Taoubi K, Köksal E. Antioxidant secoiridoids from fringe tree (Chionanthus virginicus L.). Wood Sci Technol 2008; 43: 195-212
  • 51 Bezerra BMO, Oliveira AMA, Silva CVO. Fatores inerentes às fases de creche, crescimento e terminação influenciam marcadores da atividade muscular, do metabolismo proteico e do estresse oxidativo em suínos. Rev Bras Med Vet 2016; 38: 371-376
  • 52 Aschbacher K, O'Donovan A, Wolkowitz OM, Dhabhar FS, Su Y, Epel E. Good stress, bad stress and oxidative stress: insights from anticipatory cortisol reactivity. Psychoneuroendocrinology 2013; 38: 1698-1708
  • 53 Jaguezeski AM, Glombowsky P, Galli GM. et al. Daily consumption of a homeopathic product decreases intestinal damage and stool bacterial counts in mice challenged with Escherichia coli. Microb Pathog 2020; 147: 104269
  • 54 European Commission. Council Directive 2008/120/EC of 18 December 2008 laying down mínimum standards for the protection of pigs (Codified version). Official Journal of the European Union 2009; 47: 5-13
  • 55 Zhao X, Wei C, Zhong J, Li J. Physiological functions and extraction technology of lycopene: a natural antioxidant. Izv Him 2016; 1: 153-158
  • 56 Khuda-Bukhsh AR. Towards understanding molecular mechanisms of action of homeopathic drugs: an overview. Mol Cell Biochem 2003; 253: 339-345
  • 57 Briones SF. Estudos sobre la aplicación de la homeopatia en producion animal. Santiago, Chile: 1987
  • 58 Yan L, Wang JP, Kim HJ. et al. Influence of essential oil supplementation and diets with different nutrient densities on growth performance, nutrient digestibility, blood characteristics, meat quality and fecal noxious gas content in grower–finisher pigs. Livest Sci 2010; 128: 115-122
  • 59 Lima AS. Uso de produtos homeopáticos na alimentação de suínos nas fases de crescimento e terminação [Master's dissertation]. Universidade Federal de Sergipe; 2018
  • 60 Granjo VP. Homeopatia como alternativa ao uso de antibióticos promotores de crescimento em frangos de corte [Master's dissertation]. Universidade de Londrina; 2017
  • 61 Friesen KG, Nelssen JL, Goodband RD. et al. The effect of dietary lysine on growth, carcass composition, and lipid metabolism in high-lean growth gilts fed from 72 to 136 kilograms. J Anim Sci 1995; 73: 3392-3401
  • 62 Zamora V, Figueroa JL, Reyna L, Cordero JL, Sánchez-Torres MT, Martínez M. Growth performance, carcass characteristics and blood urea nitrogen concentration of nursery pigs fed low-protein diets supplemented with glucomannans or protease. J Appl Anim Res 2011; 39: 1-4
  • 63 Meyer DJ, Harvey JW. Veterinary laboratory medicine: interpretation and diagnosis. Philadelphia: Saunders; 2004
  • 64 Boericke W. . Manual de Matéria Médica Homeopática—Tomo II—São Paulo: Robe Editorial; 2003
  • 65 Mazón-Suástegui JM, Salas-Leiva J, Teles A, Tovar-Ramírez D. Immune and antioxidant enzyme response of longfin yellowtail (Seriola rivoliana) juveniles to ultra-diluted substances derived from phosphorus, silica and pathogenic Vibrio . Homeopathy 2019; 108: 43-53
  • 66 Bora KS, Sharma A. Evaluation of antioxidant and cerebroprotective effect of Medicago sativa Linn against ischemia and reperfusion insult. Evidence-Based Complementary and Alternative Medicine. Hindawi Publishing Corporation; 2011. :1–9
  • 67 Abbruscato P, Tosi S, Crispino L. et al. Triterpenoid glycosides from Medicago sativa as antifungal agents against Pyricularia oryzae. J Agric Food Chem 2014; 62: 11030-11036
  • 68 Costa LB, Luciano FB, Miyada VS, Gois FD. Herbal extracts and organic acids as natural feed additives in pig diets. S Afr J Anim Sci 2013; 43: 181-193
  • 69 Windisch W, Schedle K, Plitzner C, Kroismayr A. Use of phytogenic products as feed additives for swine and poultry. J Anim Sci 2008; 86: E140-E148
  • 70 Jiang J, Xiong YL. Natural antioxidants as food and feed additives to promote health benefits and quality of meat products: A review. Meat Sci 2016; 120: 107-117
  • 71 Brewer MS. Natural antioxidants: sources, compounds, mechanism of action, and potential applications. Compr Rev Food Sci Food Saf 2011; 10: 221-247