Abstract
We report the onset of euglycemic diabetic ketoacidosis (EDKA) in a 20-year-old male
patient with new-onset type 2 diabetes mellitus (T2DM) 5 days after the initiation
of diet restriction and the combination of SGLT2 (sodium–glucose co-transporter 2)
inhibitors, glucagon-like peptide 1 receptor agonists, and metformin. The use of SGLT2
inhibitors in symptomatic patients with new-onset T2DM along with the extreme reduction
in carbohydrate intake might trigger the onset of EDKA. Judicious, stepwise use of
available diabetes therapies and strict monitoring can reduce the risk of this complication.
Keywords
SGLT2 inhibitors - new-onset type 2 diabetes - hyperglycemia - euglycemic - DKA -
ketoacidosis
