NLR as a Prognostic Tool in Orthopaedic Surgery in Elderly Extra-Articular Hip Fracture: A Significant Increase in NLR 24 Hours after Surgical Intervention

Laura Tomaino; Simone Pansieri; Luisella Vigna; Carlo La Vecchia; Lidia Da Lio; Gianluca Moroncini; Antonio Pompilio Gigante

doi:10.1055/s-0042-1756278

The Journal of Hip Surgery, Table of Contents

The Journal of Hip Surgery 2022; 06(03): 136-142
DOI: 10.1055/s-0042-1756278

Original Article

NLR as a Prognostic Tool in Orthopaedic Surgery in Elderly Extra-Articular Hip Fracture: A Significant Increase in NLR 24 Hours after Surgical Intervention

Authors

Laura Tomaino

¹Emergency Medicine Residency Program, Marche Polytechnic University, Ancona, Italy
Simone Pansieri

²Clinical Orthopaedics, Department of Clinical and Molecular Sciences, Università Politecnica delle Marche, Ancona, Italy
Luisella Vigna

³Department of Preventive Medicine, Occupational Health Unit “L. Devoto,” Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy
Carlo La Vecchia

⁴Department of Clinical and Community Sciences (DISSCO), Università degli Studi di Milano, Italy
Lidia Da Lio

⁵Laboratory Medicine, Azienda Ospedaliera Universitaria Ospedali Riuniti, Marche Polytechnic University, Ancona, Italy
Gianluca Moroncini

⁶Clinica Medica, Azienda Ospedaliera Universitaria Ospedali Riuniti, Marche Polytechnic University, Ancona, Italy
Antonio Pompilio Gigante

²Clinical Orthopaedics, Department of Clinical and Molecular Sciences, Università Politecnica delle Marche, Ancona, Italy

Abstract

Neutrophil-to-lymphocyte ratio (NLR) was developed as a diagnostic and prognostic tool in many medical conditions, and its use is spreading as a predictor of postoperative outcome in orthopaedic surgery. The aim of this study is to investigate the improvement of NLR 24 hours after surgical intervention in a cohort of 91 patients (F/M = 68/23) with hip fracture who underwent femur intramedullary fixation. Patients were 84.7 ± 7.9 years old, and the mean hospital stay was 13.4 ± 4.7 days, with a mean delay to surgery of 1.9 ± 1.4 days. A significant increase in NLR between baseline (T0) and 24 hours after surgical intervention (T1) was observed in the study sample overall and on subgroup analysis by gender. Nevertheless, no significant effect of NLR on the length of hospital stay was observed.

Keywords

neutrophil-to-lymphocyte ratio - trochanteric region fracture - intramedullary nail

Full Text

References

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