Int J Sports Med 2017; 38(05): 396-401
DOI: 10.1055/s-0043-101676
Behavioural Sciences
© Georg Thieme Verlag KG Stuttgart · New York

Sedentary Behavior and Arterial Stiffness in Adults with and without Metabolic Syndrome

Lucimere Bohn
1   Research Center in Physical Activity, Health and Leisure, Faculty of Sport, University of Porto, Porto, Portugal
Ana Ramoa
1   Research Center in Physical Activity, Health and Leisure, Faculty of Sport, University of Porto, Porto, Portugal
Gustavo Silva
1   Research Center in Physical Activity, Health and Leisure, Faculty of Sport, University of Porto, Porto, Portugal
Nuno Silva
2   Department of Biochemistry, Porto, University of Porto Faculty of Medicina, Portugal
Sandra Marlene Abreu
3   Education and Sport, Faculty of Psychology, Lusófona University of Porto, Porto, Portugal
Fernando Ribeiro
4   School of Health Sciences and Institute of Biomedicine- iBiMED, University of Aveiro, Aveiro, Portugal
Pierre Boutouyrie
5   Pharmacology Department and INSERM U 970, Hopital Europeen Georges Pompidou, Paris, France
Stéphane Laurent
5   Pharmacology Department and INSERM U 970, Hopital Europeen Georges Pompidou, Paris, France
José Oliveira
1   Research Center in Physical Activity, Health and Leisure, Faculty of Sport, University of Porto, Porto, Portugal
› Author Affiliations
Further Information

Publication History

accepted after revision 26 October 2016

Publication Date:
09 May 2017 (online)


This study aimed to investigate whether sedentary time (Sed) and physical activity (PA) are associated with arterial stiffness in individuals with and without metabolic syndrome (MetS). This cross-sectional study comprised 197 individuals (47±13 years; 58% female) from a primary health care centre. Arterial stiffness was assessed using carotid-femoral pulse wave velocity (cfPWV). Metabolic syndrome was determined as clustering of at least 3 out of 5 risk factors (central obesity, hypertension, impaired glucose, triglycerides and high-density lipoprotein cholesterol). Daily PA was objectively assessed and classified in Sed, light and moderate-to-vigorous PA. Physical activity was used as a continuous variable for multiple regression analysis. For mean comparisons of cfPWV between subjects with and without MetS, a binary split at the median of Sed and PA was used. Sedentary time was associated with cfPWV (β=0.11; p=0.01) explaining 1.3% of its variance; independently of age (β=0.49; p<0.001), systolic blood pressure (β=0.27; p<0.001) and fasting glucose (β=0.19; p<0.001). Participants with MetS and more Sed had higher cfPWV than those with MetS and less Sed (9.9±1.0 vs. 8.9±1.0 m/s; p<0.05). Sedentary time is associated with cfPWV independently of age and metabolic risk factors. A higher Sed in MetS individuals lead to a worse arterial stiffness profile.

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