Endoscopy 2017; 49(06): 609-610
DOI: 10.1055/s-0043-107611
© Georg Thieme Verlag KG Stuttgart · New York

Endoluminal appendectomy: the first description in humans for acute appendicitis

Everson L. A. Artifon, Ricardo Sato Uemura, Carlos Kiyoshi Furuya Júnior, Carolina Manna Santos, Diego Soares Coca, Hugo Gonçalo Guedes, José Pinhata Otoch
  • Division of Gastrointestinal Endoscopy, Ana Costa Hospital, Santos, Brazil
Further Information

Publication History

Publication Date:
02 May 2017 (eFirst)

Appendix inversion into the cecal lumen can be demonstrated, and its endoluminal appendectomy is feasible [1]. We describe the first procedure to remove the appendix using colonoscopy during acute appendicitis presentation.

A video colonoscope (Pentax Medical, Tokyo, Japan) and a handmade double-channel colonoscope prototype with an adapted 20 Fr nasogastric tube were used for the colonoscopy ([Fig. 1]). Shark Tooth grasping forceps (Olympus Medical Systems, Tokyo, Japan), an endoloop (Olympus), a standard diathermic snare wire loop (Boston Scientific Corp., Marlborough, Massachusetts, USA), and endoclips (Olympus) were also used. Owing to such an unconventional procedure, informed consent was obtained from the patient’s wife and from his surgeon after the colonoscopic findings during the same procedure.

Zoom Image
Fig. 1 The handmade colonoscope prototype, consisting of a double-channel endoscope with Shark Tooth grasping forceps (Olympus Medical Systems, Tokyo, Japan) and a 20 Fr nasogastric tube for endoloop passage.

A 67-year-old man with transverse colostomy secondary to surgical resection of a prior obstructive sigmoid neoplasm, presented with vague lower abdominal pain and fever. Two days earlier, an ultrasonography showed an enlarged appendix. A colonoscopy was performed to investigate synchronic lesions and showed only a purulent discharge from the appendiceal orifice.

The endoloop from the attached nasogastric tube was opened and positioned close to the appendiceal orifice. The Shark Tooth grasping forceps was passed through the endoloop and gently into the appendix until tissue resistance was detected. The appendix tip was grasped and inverted back into the lumen in a single pull-through motion ([Video 1]). The appendix presented with a reddish orange mucosa in its tail. A diathermic snare wire loop (Blend 1, 30 W) was then placed over the inverted appendix to cut. Another endoloop was loaded, and then endoclips were used to fix the ligating loop into position and close the ligated appendix base ([Fig. 2], [Video 1]). No bleeding was observed.

Video 1 Removal of the appendix using colonoscopy in a case of acute appendicitis. We inverted the appendix in a single pull-through motion. An endoloop was loaded before and after the appendix was resected using a diathermic snare. Pathological assessment confirmed acute appendicitis.

Georg Thieme Verlag. Please enable Java Script to watch the video.
Zoom Image
Fig. 2 Endoluminal appendectomy – endoscopic view. a Inversion of the appendix using grasping forceps. b Endoloop positioning over the base of the inverted appendix. c Cutting the base with a snare loop. d – f The resected area of the appendix was closed using hemostatic clips.

Pathological assessment confirmed acute appendicitis ([Fig. 3]).

Zoom Image
Fig. 3 Pathological assessment showed inflammatory cells in the submucosa (hematoxylin and eosin staining).

The patient experienced abdominal discomfort and low-grade fever on the first postoperative day. He received ceftriaxone 2 g/day and metronidazole 1.5 g/day for 2 days; oral diet was started on the same day. On the second postoperative day, the patient’s condition improved, without any report of pain.


Endoscopy E-Videos is a free access online section, reporting on interesting cases and new techniques in gastroenterological endoscopy. All papers include a high quality video and all contributions are freely accessible online.
This section has its own submission website athttps://mc.manuscriptcentral.com/e-videos