Endoluminal appendectomy: the first description in humans for acute appendicitis
02 May 2017 (eFirst)
Appendix inversion into the cecal lumen can be demonstrated, and its endoluminal appendectomy is feasible . We describe the first procedure to remove the appendix using colonoscopy during acute appendicitis presentation.
A video colonoscope (Pentax Medical, Tokyo, Japan) and a handmade double-channel colonoscope prototype with an adapted 20 Fr nasogastric tube were used for the colonoscopy ([Fig. 1]). Shark Tooth grasping forceps (Olympus Medical Systems, Tokyo, Japan), an endoloop (Olympus), a standard diathermic snare wire loop (Boston Scientific Corp., Marlborough, Massachusetts, USA), and endoclips (Olympus) were also used. Owing to such an unconventional procedure, informed consent was obtained from the patient’s wife and from his surgeon after the colonoscopic findings during the same procedure.
A 67-year-old man with transverse colostomy secondary to surgical resection of a prior obstructive sigmoid neoplasm, presented with vague lower abdominal pain and fever. Two days earlier, an ultrasonography showed an enlarged appendix. A colonoscopy was performed to investigate synchronic lesions and showed only a purulent discharge from the appendiceal orifice.
The endoloop from the attached nasogastric tube was opened and positioned close to the appendiceal orifice. The Shark Tooth grasping forceps was passed through the endoloop and gently into the appendix until tissue resistance was detected. The appendix tip was grasped and inverted back into the lumen in a single pull-through motion ([Video 1]). The appendix presented with a reddish orange mucosa in its tail. A diathermic snare wire loop (Blend 1, 30 W) was then placed over the inverted appendix to cut. Another endoloop was loaded, and then endoclips were used to fix the ligating loop into position and close the ligated appendix base ([Fig. 2], [Video 1]). No bleeding was observed.
Video 1 Removal of the appendix using colonoscopy in a case of acute appendicitis. We inverted the appendix in a single pull-through motion. An endoloop was loaded before and after the appendix was resected using a diathermic snare. Pathological assessment confirmed acute appendicitis.
Pathological assessment confirmed acute appendicitis ([Fig. 3]).
The patient experienced abdominal discomfort and low-grade fever on the first postoperative day. He received ceftriaxone 2 g/day and metronidazole 1.5 g/day for 2 days; oral diet was started on the same day. On the second postoperative day, the patient’s condition improved, without any report of pain.
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- 1 Silberhumer GR, Birsan T, Noda W. et al. Design and instrumentation of new devices for performing appendectomy at colonoscopy (with video). Gastrointest Endosc 2008; 68: 139-145