Int J Sports Med 2018; 39(01): 29-36
DOI: 10.1055/s-0043-119222
Training & Testing
© Georg Thieme Verlag KG Stuttgart · New York

Concurrent Training with Blood Flow Restriction does not Decrease Inflammatory Markers

Thiago Mattos Frota de Souza1, *, Cleiton Augusto Libardi2, *, Cláudia Regina Cavaglieri1, Arthur Fernandes Gáspari1, Diego Trevisan Brunelli1, Giovana Vergínia de Souza1, Carlos Ugrinowitsch3, Li Min Li4, Mara Patricia Traina Chacon-Mikahil1
  • 1Faculty of Physical Education, University of Campinas, UNICAMP, Campinas, Brazil
  • 2Department of Physical Education, Federal University of São Carlos - UFSCar, São Carlos, Brazil
  • 3School of Physical Education and Sport, University of São Paulo, USP, São Paulo, Brazil
  • 4Department of Neurology, University of Campinas, UNICAMP, Campinas, Brazil
Further Information

Publication History

accepted 18 August 2017

Publication Date:
09 November 2017 (eFirst)


The aging process is associated with several changes in the elderly such as the decrease in cardiorespiratory fitness, strength and muscle mass, in addition to chronic low-grade inflammation. Concurrent training with blood flow restriction can be an interesting alternative to improve functional capacity with low mechanical stress in the elderly. The purpose of this study was to compare the inflammatory effects in older individuals submitted to two different protocols of concurrent training. Twenty-two healthy older adults (63.7±3.8 years; 69.8±8.9 kg; 1.6±0.1 m) performed 12 weeks of concurrent training (CT) or concurrent training with blood flow restriction (CTBFR) and the effects on inflammatory markers were analyzed. We found inflammatory behavior for the CTBFR group with a significant difference in serum concentration of C-reactive protein between pre- and post-moment (0.96±0.37 to 1.71±1.45, p=0.049), with no difference between groups, and a time effect in interleukin-6 (pre=0.86±0.43; post=1.02±0.46, p=0.016). We conclude that the CTBFR showed a pro-inflammatory profile after the period of intervention whereas the CT showed the opposite.

* these authors contributed equally to this work and should be considered co-first authors.