Abstract
In this study, we aim to clarify the influence based on bone resorption markers at
onset of stress fracture. Also, we will clarify the state of the bone resorption markers
of female long distance runners who have a history of stress fracture and also ones
who routinely practices running long distances. Participants comprised 19 female long
distance athletes. The survey period was 2011–2014, and we measured u-NTX as a bone
resorption marker at least twice a year, taking the mean±SD of the periodic measured
values without stress fracture as the mean value. Measurements were collected sample
when stress fractures developed. 132 u-NTX measurements were taken from 19 participants.
As a result, the average was 41.03±12.31 nmolBCE/mmolCRE (Q1: 33.15, Q2: 40.55, Q3:
47.95). In six of the 19 participants, u-NTX could be measured following a stress
fracture. The mean value of u-NTX for those participants was 40.16±9.10 nmolBCE/mmolCRE,
increasing to 64.08±16.07 nmolBCE/mmol CRE with the stress fracture (p<0.01). The
findings showed that, in adult female long distance runners, u-NTX values when there
was no stress fracture were within the standard value for mean premenopausal women,
but increased when the athletes suffered from a stress fracture.
Key words
bone injury - bone turnover marker - female athletes - early diagnosis
