Neurology International Open 2017; 01(04): E312-E315
DOI: 10.1055/s-0043-119865
New Developments in Neurology
© Georg Thieme Verlag KG Stuttgart · New York

New Results on Brain Stimulation in Chronic Pain

Andrea Antal
Department of Clinical Neurophysiology
Walter Paulus
Department of Clinical Neurophysiology
Veit Rohde
Department of Neurosurgery, University Medical Center, Georg-August University, Göttingen, Germany
› Author Affiliations
Further Information

Publication History

Publication Date:
09 November 2017 (online)


Pain that has become chronic has lost its warning function and is associated with dysfunction of the so-called pain network. Systematic brain stimulation aims to normalize this network by modulating neuronal activities. Non-invasive DC stimulation (tDCS) or repetitive transcranial magnetic stimulation (rTMS) are considered effective in pain treatment. Here, the stimulation of the primary motor cortex (M1) plays a central role. If the pain is not adequately controlled by tDCS and rTMS, invasive procedures such as motor cortex stimulation (MCS) or deep brain stimulation are available as a last resort.