Endoscopy 2018; 50(01): 63-68
DOI: 10.1055/s-0043-120666
Innovations and brief communications
© Georg Thieme Verlag KG Stuttgart · New York

Feasibility, safety, and diagnostic yield of the Extra Wide Angle View (EWAVE) colonoscope for the detection of colorectal lesions

Maxime E. S. Bronzwaer1, Evelien Dekker1, 2, Vincens Weingart3, Stefan Groth4, Mathieu Pioche5, Jérôme Rivory5, Torsten Beyna6, Horst Neuhaus6, Thierry Ponchon5, Hans Allescher3, Paul Fockens1, 2, Thomas Rösch4
  • 1Department of Gastroenterology and Hepatology, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands
  • 2Department of Endoscopy, Bergman Inwendige Zorg Amsterdam (IZA), Amsterdam, The Netherlands
  • 3Medical Department, Klinikum Garmisch-Partenkirchen, Ludwig-Maximilians University, Garmisch-Partenkirchen, Germany
  • 4Department of Interdisciplinary Endoscopy, University Hospital Hamburg-Eppendorf, University of Hamburg, Hamburg, Germany
  • 5Department of Endoscopy and Gastroenterology, Hôpital Edouard Herriot, University of Lyon, Lyon, France
  • 6Department of Gastroenterology and Hepatology, Evangelischen Krankenhaus Düsseldorf, Düsseldorf, Germany
TRIAL REGISTRATION: Prospective Multi-Center Cohort Study NTR 4536 at trialregister.nl
Further Information

Publication History

submitted 27 March 2017

accepted after revision 09 July 2017

Publication Date:
13 November 2017 (eFirst)


Background and study aims The adenoma detection rate (ADR) of conventional colonoscopy can still be improved. We conducted a prospective multicenter cohort study to assess the feasibility, safety, and diagnostic yield of the Extra Wide Angle View (EWAVE) colonoscope, which offers a 235° view obtained from a forward-viewing and two lateral backward-viewing lenses incorporated into one image.

Patients and methods The study was performed between November 2015 and June 2016. EWAVE colonoscopy was performed in patients with an increased risk of colorectal cancer by experienced and EWAVE-trained endoscopists (≥ 500 colonoscopies, ≥ 10 with the EWAVE system).

Results A total of 193 patients underwent EWAVE colonoscopy. The cecal intubation rate was 97.4 %. EWAVE colonoscopy had a polyp detection rate (PDR) of 61.1 % (118 /193), ADR of 39.9 % (77 /193), and advanced ADR of 13.5 % (26 /193). No adverse events occurred.

Conclusions EWAVE colonoscopy is feasible and safe. The ADR appears comparable to those achieved with conventional colonoscopes in similar patient populations. To further elucidate the additional benefits of wide-angle-view colonoscopes, randomized trials would be required.