Endoscopy 2018; 50(01): 63-68
DOI: 10.1055/s-0043-120666
Innovations and brief communications
© Georg Thieme Verlag KG Stuttgart · New York

Feasibility, safety, and diagnostic yield of the Extra Wide Angle View (EWAVE) colonoscope for the detection of colorectal lesions

Maxime E. S. Bronzwaer
Department of Gastroenterology and Hepatology, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands
,
Evelien Dekker
Department of Gastroenterology and Hepatology, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands
Department of Endoscopy, Bergman Inwendige Zorg Amsterdam (IZA), Amsterdam, The Netherlands
,
Vincens Weingart
Medical Department, Klinikum Garmisch-Partenkirchen, Ludwig-Maximilians University, Garmisch-Partenkirchen, Germany
,
Stefan Groth
Department of Interdisciplinary Endoscopy, University Hospital Hamburg-Eppendorf, University of Hamburg, Hamburg, Germany
,
Mathieu Pioche
Department of Endoscopy and Gastroenterology, Hôpital Edouard Herriot, University of Lyon, Lyon, France
,
Jérôme Rivory
Department of Endoscopy and Gastroenterology, Hôpital Edouard Herriot, University of Lyon, Lyon, France
,
Torsten Beyna
Department of Gastroenterology and Hepatology, Evangelischen Krankenhaus Düsseldorf, Düsseldorf, Germany
,
Horst Neuhaus
Department of Gastroenterology and Hepatology, Evangelischen Krankenhaus Düsseldorf, Düsseldorf, Germany
,
Thierry Ponchon
Department of Endoscopy and Gastroenterology, Hôpital Edouard Herriot, University of Lyon, Lyon, France
,
Hans Allescher
Medical Department, Klinikum Garmisch-Partenkirchen, Ludwig-Maximilians University, Garmisch-Partenkirchen, Germany
,
Paul Fockens
Department of Gastroenterology and Hepatology, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands
Department of Endoscopy, Bergman Inwendige Zorg Amsterdam (IZA), Amsterdam, The Netherlands
,
Thomas Rösch
Department of Interdisciplinary Endoscopy, University Hospital Hamburg-Eppendorf, University of Hamburg, Hamburg, Germany
› Author Affiliations
TRIAL REGISTRATION: Prospective Multi-Center Cohort Study NTR 4536 at trialregister.nl
Further Information

Publication History

submitted 27 March 2017

accepted after revision 09 July 2017

Publication Date:
13 November 2017 (eFirst)

Abstract

Background and study aims The adenoma detection rate (ADR) of conventional colonoscopy can still be improved. We conducted a prospective multicenter cohort study to assess the feasibility, safety, and diagnostic yield of the Extra Wide Angle View (EWAVE) colonoscope, which offers a 235° view obtained from a forward-viewing and two lateral backward-viewing lenses incorporated into one image.

Patients and methods The study was performed between November 2015 and June 2016. EWAVE colonoscopy was performed in patients with an increased risk of colorectal cancer by experienced and EWAVE-trained endoscopists (≥ 500 colonoscopies, ≥ 10 with the EWAVE system).

Results A total of 193 patients underwent EWAVE colonoscopy. The cecal intubation rate was 97.4 %. EWAVE colonoscopy had a polyp detection rate (PDR) of 61.1 % (118 /193), ADR of 39.9 % (77 /193), and advanced ADR of 13.5 % (26 /193). No adverse events occurred.

Conclusions EWAVE colonoscopy is feasible and safe. The ADR appears comparable to those achieved with conventional colonoscopes in similar patient populations. To further elucidate the additional benefits of wide-angle-view colonoscopes, randomized trials would be required.