Endoscopic mucosal resection of rectal squamous cell papilloma
19 January 2018 (eFirst)
A 22-year-old male patient presented with a 3-month history of persistent, colicky, lower abdominal pain. He was referred for colonoscopy. Total colonoscopy showed multiple small-to-medium sized pale pink, nonulcerated, polypoid lesions in the distal part of the rectum, occupying most of the circumference ([Fig. 1]).
The patient’s medical history was not significant. After discussing his sexual history, he mentioned having a male partner for 2 years. Basic investigations were carried out, including human immunodeficiency virus serology; they were all negative. After discussing the treatment options with the patient, endoscopic mucosal resection of the lesions was performed ([Fig. 2], [Video 1]). Histopathological examination showed squamous cell papillomatosis of the rectum, with mild-to-moderate atypia ([Fig. 3]). Isolation of the human papilloma virus (HPV) from the specimen was not possible.
Video 1 Endoscopic mucosal resection of rectal squamous cell papilloma.
Squamous cell papilloma (SCP) is a benign lesion that is a result of infection with HPV . HPV-associated diseases are sexually transmitted and mainly affect the genitals, causing wart formation . SCP arises from the stratified squamous epithelium of the skin, lip, oral cavity, tongue, pharynx, larynx, esophagus, cervix, vagina or anal canal . SCP of the gastrointestinal tract is mainly localized to the oropharynx, esophagus, and anal canal . The current case was an extremely rare case of rectal SCP.
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