CC BY-NC-ND 4.0 · Journal of Diabetes and Endocrine Practice 2023; 06(01): 011-016
DOI: 10.1055/s-0043-1763272
Original Article

Prevalence of Cardiovascular Risk Factors and Associated Estimated Risk of Atherosclerotic Cardiovascular Disease in Adult Volunteers in Jeddah, Saudi Arabia

Nabeel H. Ismaeil
1   Department Cardiovascular, King Faisal Specialist Hospital & Research Center, Riyadh, Saudi Arabia
,
Ammar G. Chaudhary
2   Department Cardiovascular Diseases, King Faisal Specialist Hospital & Research Center, Jeddah, Saudi Arabia
,
Nasser A. Mahdi
3   Medicine, King Faisal Specialist Hospital & Research Center, Jeddah, Saudi Arabia
,
Adel M. Al-Hyari
4   Obesity, Endocrine and Metabolic Center, King Faisal Specialist Hospital & Research Center, Saudi Arabia
,
Naji Aljohani
5   Obesity, Endocrine and Metabolic Center King Fahad Medical City, Saudi Arabia
› Author Affiliations
Funding and Sponsorship None.

Abstract

Background The prevalence of cardiovascular disease and its risk factors are rising globally, including in the Kingdom of Saudi Arabia (KSA). The majority of epidemiologic data, however, was obtained from primary care centers or tertiary hospitals, and disease epidemiology in the general population needs to be better defined.

Objective: This study aims to determine the prevalence of cardiometabolic risk factors in a random sample of adult volunteers in Jeddah, Saudi Arabia, and their risk for atherosclerotic cardiovascular disease (ASCVD).

Materials and Methods This cross-sectional study was based on data from volunteers participating in the “My Heart, My Health” community campaign conducted in a large-scale commercial center in Jeddah, KSA. Participants 20 years of age and above answered a questionnaire containing several risk factors of ASCVD. Anthropometric measurements and blood samples were collected for lipid profile and hemoglobin A1c. Ten-year and lifelong ASCVD risk scores were calculated.

Results Eight-hundred seven volunteers participated (390 men and 417 women). The most common risk factor for men was low-high-density lipoprotein cholesterol, which was more prevalent than in women (77.9 vs. 30.3%, p < 0.01). The most common risk factor for women was obesity that was more prevalent than for men (42.6 vs. 36.8%, p = 0.30). The mean ASCVD risk score in 10 years was 8.1% (standard deviation [SD]: 10.5), and the mean ASCVD risk factor optimization % was 2.0% (SD: 2.5). The mean lifelong risk score was 39.5% (SD: 13.9), and the mean ASCVD lifelong risk factor optimization was 6.6% (SD: 2.6).

Conclusion This study identified a high prevalence of cardiometabolic risk factors in the Saudi general public visiting a large commercial center in Jeddah, Saudi Arabia. The leading cardiometabolic risk factor is dyslipidemia in men and obesity in women. The 10-year ASCVD risk factor score is modest.

Authors' Contributions

All the named authors have participated in the conception of the study and data analysis. They all contributed to the drafting and revising of the manuscript.


Compliance with Ethical Principles

Ethical approval was obtained from the College of Science, King Saud University, Riyadh, Saudi Arabia




Publication History

Article published online:
05 April 2023

© 2023. Gulf Association of Endocrinology and Diabetes (GAED). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

Thieme Medical and Scientific Publishers Pvt. Ltd.
A-12, 2nd Floor, Sector 2, Noida-201301 UP, India

 
  • References

  • 1 Barquera S, Pedroza-Tobías A, Medina C. et al. Global overview of the epidemiology of the atherosclerotic cardiovascular disease. Arch Med Res 2015; 46 (05) 328-338
  • 2 Yatsuya H, Li Y, Hilawe EH. et al. Global trend in overweight and obesity and its association with cardiovascular disease incidence. Circ J 2014; 78 (12) 2807-2818
  • 3 Ahmed AM, Hersi A, Mashhoud W. et al. Cardiovascular risk factors burden in Saudi Arabia: the Africa Middle East Cardiovascular Epidemiological (ACE) study. J Saudi Heart Assoc 2017; 29 (04) 235-243
  • 4 Amer OE, Sabico S, Khattak MNK. et al. Increasing prevalence of pediatric metabolic syndrome and its components among Arab youth: a time-series study from 2010-2019. Children (Basel) 2021; 8 (12) 1129
  • 5 Alharthi FS, Alrahimi JS, Alotaibi AA, Alhamdi DA, Ibrahim BM, Badeeb YA. Prevalence of undiagnosed cardiovascular risk factors in adults aged 20–40: a cross-sectional study in 2016 in Jeddah, Saudi Arabia. Cardiol Res 2017; 8 (03) 111-116
  • 6 Al-Daghri NM, Al-Attas OS, Alokail MS. et al. Diabetes mellitus type 2 and other chronic non-communicable diseases in the central region, Saudi Arabia (Riyadh cohort 2): a decade of an epidemic. BMC Med 2011; 9: 76
  • 7 Al-Daghri NM, Hussain SD, Ansari MGA. et al. Decreasing prevalence of vitamin D deficiency in the central region of Saudi Arabia (2008-2017). J Steroid Biochem Mol Biol 2021; 212: 105920
  • 8 Al-Daghri NM, Rahman S, Sabico S. et al. Association of vitamin B12 with pro-inflammatory cytokines and biochemical markers related to cardiometabolic risk in Saudi subjects. Nutrients 2016; 8 (09) 460
  • 9 Al-Daghri NM, Sabico S, Ansari MGA. et al. Endotoxemia, vitamin D and premature biological ageing in Arab adults with different metabolic states. Saudi J Biol Sci 2022; 29 (06) 103276
  • 10 Al-Disi D, Ansari MGA, Sabico S. et al. High glucose load and endotoxemia among overweight and obese Arab women with and without diabetes: an observational study. Medicine (Baltimore) 2020; 99 (46) e23211
  • 11 Alshaikh MK, Filippidis FT, Al-Omar HA, Rawaf S, Majeed A, Salmasi AM. The ticking time bomb in lifestyle-related diseases among women in the Gulf Cooperation Council countries; review of systematic reviews. BMC Public Health 2017; 17 (01) 536
  • 12 Al-Hamdan R, Avery A, Al-Disi D, Sabico S, Al-Daghri NM, McCullough F. Efficacy of lifestyle intervention program for Arab women with prediabetes using social media as an alternative platform of delivery. J Diabetes Investig 2021; 12 (10) 1872-1880
  • 13 Amer OE, Sabico S, Alfawaz HA. et al. Reversal of prediabetes in Saudi Adults: results from an 18 month lifestyle intervention. Nutrients 2020; 12 (03) 804
  • 14 Al-Daghri NM, Amer OE, Khattak MNK. et al. Effects of different vitamin D supplementation strategies in reversing metabolic syndrome and its component risk factors in adolescents. J Steroid Biochem Mol Biol 2019; 191: 105378
  • 15 Goff Jr DC, Lloyd-Jones DM, Bennett G. et al. 2013 ACC/AHA guideline on the assessment of cardiovascular risk: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol 2014; 63 (25 Pt B): 2935-2959
  • 16 Al-Daghri NM, Al-Attas OS, Alokail MS, Alkharfy KM, Sabico SL, Chrousos GP. Decreasing prevalence of the full metabolic syndrome but a persistently high prevalence of dyslipidemia among adult Arabs. PLoS One 2010; 5 (08) e12159
  • 17 Moon JH, Koo BK, Moon MK. Optimal high-density lipoprotein cholesterol cutoff for predicting cardiovascular disease: comparison of the Korean and US National Health and Nutrition Examination Surveys. J Clin Lipidol 2015; 9 (03) 334-342
  • 18 Topel ML, Shen J, Morris AA. et al. Comparisons of the Framingham and pooled cohort equation risk scores for detecting subclinical vascular disease in blacks versus whites. Am J Cardiol 2017; [Epub ahead of print]
  • 19 Al-Zakwani I, Al Mahmeed W, Shehab A. et al. Impact of metabolic syndrome on lipid target achievements in the Arabian Gulf: findings from the CEPHEUS study. Diabetol Metab Syndr 2016; 8: 49
  • 20 Abazid R, Al Saqqa H, Smettei O. Analysis of three risk stratification systems in a Saudi population. J Saudi Heart Assoc 2017; 29 (02) 96-101
  • 21 Aljasir BA, Al-Mugti HS, Alosaimi MN, Al-Mugati AS. Evaluation of the National Guard Health Promotion Program for Chronic Diseases and Comorbid Conditions Among Military Personnel in Jeddah City, Saudi Arabia, 2016. Mil Med 2017; 182 (11) e1973-e1980
  • 22 Alquaiz AM, Kazi A, Qureshi R, Siddiqui AR, Jamal A, Shaik SA. Correlates of cardiovascular disease risk scores in women in Riyadh, Kingdom of Saudi Arabia. Women Health 2015; 55 (01) 103-117
  • 23 Soofi MA, Youssef MA. Prediction of 10-year risk of hard coronary events among Saudi adults based on prevalence of heart disease risk factors. J Saudi Heart Assoc 2015; 27 (03) 152-159
  • 24 Potestio ML, McLaren L, Robinson Vollman A, Doyle-Baker PK. Childhood obesity: perceptions held by the public in Calgary, Canada. Can J Public Health 2008; 99 (02) 86-90