Geburtshilfe und Frauenheilkunde, Inhaltsverzeichnis Geburtshilfe Frauenheilkd 2023; 83(06): 734-735DOI: 10.1055/s-0043-1768836 Abstracts | BGGF & OEGG 2023 Poster Gynäkologische Onkologie Etablierung eines SIS-Gerüst basierten 3D-Gewebemodells des humanen Peritoneums zur Untersuchung der Dissemination von Ovarialkarzinomzellen Authors Institutsangaben S-L Herbert 1 Frauenklinik und Poliklinik, Universitätsklinikum Würzburg, Würzburg A Fick 1 Frauenklinik und Poliklinik, Universitätsklinikum Würzburg, Würzburg M Heydarian 2 Biozentrum, Abteilung für Mikrobiologie, Universität Würzburg, Würzburg M Metzger 3 Lehrstuhl für Tissue Engineering, Universitätsklinikum Würzburg, Würzburg 4 Fraunhofer ISC, Translationszentrum für Regenerative Therapien TLZ-RT, Würzburg A Wöckel 1 Frauenklinik und Poliklinik, Universitätsklinikum Würzburg, Würzburg Th Rudel 2 Biozentrum, Abteilung für Mikrobiologie, Universität Würzburg, Würzburg V Kozjak-Pavlovic 1 2 Biozentrum, Abteilung für Mikrobiologie, Universität Würzburg, Würzburg C Wulff 1 Frauenklinik und Poliklinik, Universitätsklinikum Würzburg, Würzburg 5 Diese Autoren haben gleichermaßen beigetragen Artikel empfehlen Abstract Volltext Referenzen Literatur 1 Steinke M, Gross R, Walles H. et al. An engineered 3D human airway mucosa model based on an SIS scaffold. Biomaterials 2014; 35: 7355-7362 2014/06/11 2 Schweinlin M, Rossi A, Lodes N. et al. Human barrier models for the in vitro assessment of drug delivery. Drug delivery and translational research 2017; 7: 217-227 2016/08/24 3 Heydarian M, Yang T, Schweinlin M. et al. Biomimetic Human Tissue Model for Long-Term Study of Neisseria gonorrhoeae Infection. Frontiers in Microbiology 2019; 10: 1740-1740 4 Kenny HA, Krausz T, Yamada SD. et al. Use of a novel 3D culture model to elucidate the role of mesothelial cells, fibroblasts and extra-cellular matrices on adhesion and invasion of ovarian cancer cells to the omentum. International Journal of Cancer 2007; 121: 1463-1472 2007/06/05 5 Asano Y, Odagiri T, Oikiri H. et al. Construction of artificial human peritoneal tissue by cell-accumulation technique and its application for visualizing morphological dynamics of cancer peritoneal metastasis. Biochemical and biophysical research communications 2017; 494: 213-219 2017/10/17 6 Bekes I, Löb S, Holzheu I. et al. Nectin-2 in ovarian cancer: How is it expressed and what might be its functional role?. Cancer Science 2019; 110: 1872-1882 2019/05/02 7 Kenny HA, Krausz T, Yamada SD. et al. Use of a novel 3D culture model to elucidate the role of mesothelial cells, fibroblasts and extra-cellular matrices on adhesion and invasion of ovarian cancer cells to the omentum. International Journal of Cancer 2007; 121: 1463-1472 8 Shi L, Ronfard V.. Biochemical and biomechanical characterization of porcine small intestinal submucosa (SIS): a mini review. International Journal of Burns and Trauma 2013; 3: 173-179 9 Kenny HA, Dogan S, Zillhardt M. et al. Organotypic models of metastasis: A three-dimensional culture mimicking the human peritoneum and omentum for the study of the early steps of ovarian cancer metastasis. Cancer Treatment and Research 2009; 149: 335-351 2009/09/19 10 Asano Y, Nishiguchi A, Matsusaki M. et al. Ultrastructure of blood and lymphatic vascular networks in three-dimensional cultured tissues fabricated by extracellular matrix nanofilm-based cell accumulation technique. Microscopy 2014; 63: 219-226 11 Bekes I, Friedl TW, Köhler T. et al. Does VEGF facilitate local tumor growth and spread into the abdominal cavity by suppressing endothelial cell adhesion, thus increasing vascular peritoneal permeability followed by ascites production in ovarian cancer?. Molecular cancer 2016; 15: 13 2016/02/13 12 Herr D, Sallmann A, Bekes I. et al. VEGF induces ascites in ovarian cancer patients via increasing peritoneal permeability by downregulation of Claudin 5. Gynecologic oncology 2012; 127: 210-216 2012/05/15