Analysis of pachymic acid and dehydropachymic acid of Pachyma hoelen collected in Korea

The sclerotia of Pachyma hoelen (Bokryeong) which belong to Polyporaceae, are one of the most important crude drugs in traditional medicine and health food in Korea. It is used for sedative, diuretic and tonic effects. Among the many compounds, pachymic acid (PA) and dehydropachymic acid (DPA) are the main triterpenes isolated from P. hoelen. Because PA and DPA are recognized as marker compounds of P. hoelen, we measured the contents of these two compounds for selecting superior ones. In this study, we evaluate the characteristics and measured the content of PA and DPA in the bark and inside skin of the sclerotia of P. hoelen collected in Korea. Using HPLC, two major triterpene acids including PA and DPA, in the sclerotia of

P. hoelen were evaluated. The results findings were that the contents of PA and DPA in the bark and the inside skin of the sclerotia of P. hoelen collected from Hongchun were 2.82±0.1 mg/g and 1.03±0.1mg/g for PA, and 7.37±0.2 mg/g and 2.83±0.1mg/g for DPA, respectively. On the other hand, the contents of PA and DPA in the bark and the inside skin of the sclerotia of P. hoelen from Chungju were 2.75±0.1 mg/g and

2.01±0.1mg/g for PA, and 8.55±0.2 mg/g and 4.12±0.1mg/g for DPA, respectively. The content of PA and DPA in P. hoelen were in the range of 1.03 – 5.94 mg/g and 2.83 – 10.92 mg/g, respectively.

Publication History

Article published online:
16 November 2023