CC BY-NC-ND 4.0 · Journal of Fetal Medicine 2023; 10(02): 076-081
DOI: 10.1055/s-0043-57038
Case Report

The Course, Prognosis, and Hand-Holding of Parents in Nonimmune Hydrops Fetalis—A Case Report with a Brief Review

1   Department of Obstetrics and Gynecology, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India
1   Department of Obstetrics and Gynecology, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India
2   Department of Neonatology, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India
1   Department of Obstetrics and Gynecology, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India
› Author Affiliations
Funding None.


Hydrops fetalis (HF) is a serious fetal condition characterized by abnormal accumulation of fluid in fetal soft tissues and serous cavities. HF can be immune hydrops fetalis (IHF) or nonimmune hydrops fetalis (NIHF) depending upon the presence of antibodies in the mother. We report a case of euploid NIHF who delivered at 34 weeks and had spontaneous recovery. The baby had gross fetal ascites and mild pleural and pericardial effusion. After a thorough workup, no definite cause could be found. However, the ascites spontaneously resolved. The baby had many peaks and valleys during the initial 3 months of life, doing well at 6 months of age and is under follow-up. This case report highlights the practical workup and diagnostic algorithm of NIHF and provides an updated review.

Authors' Contributions

C.S. designed the concept. D.C. and S.B. helped in literature search. S.K.C. managed the patient and helped in literature search and editing the manuscript. D.C. and C.S. wrote the manuscript. All of the authors read and approved the final manuscript.

Publication History

Article published online:
12 May 2023

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