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The Course, Prognosis, and Hand-Holding of Parents in Nonimmune Hydrops Fetalis—A Case Report with a Brief ReviewFunding None.
Hydrops fetalis (HF) is a serious fetal condition characterized by abnormal accumulation of fluid in fetal soft tissues and serous cavities. HF can be immune hydrops fetalis (IHF) or nonimmune hydrops fetalis (NIHF) depending upon the presence of antibodies in the mother. We report a case of euploid NIHF who delivered at 34 weeks and had spontaneous recovery. The baby had gross fetal ascites and mild pleural and pericardial effusion. After a thorough workup, no definite cause could be found. However, the ascites spontaneously resolved. The baby had many peaks and valleys during the initial 3 months of life, doing well at 6 months of age and is under follow-up. This case report highlights the practical workup and diagnostic algorithm of NIHF and provides an updated review.
Keywordsabsent nasal bone - exome sequencing - fetal ascites - Griscelli's syndrome - lymphatic dysplasia - nonimmune hydrops fetalis
C.S. designed the concept. D.C. and S.B. helped in literature search. S.K.C. managed the patient and helped in literature search and editing the manuscript. D.C. and C.S. wrote the manuscript. All of the authors read and approved the final manuscript.
Article published online:
12 May 2023
© 2023. Society of Fetal Medicine. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)
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