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CC BY 4.0 · Rev Bras Ortop (Sao Paulo) 2024; 59(06): e830-e838
DOI: 10.1055/s-0044-1779321
Revisão Sistemática
Oncologia

Clinical Outcomes of Curettage versus Surgical Resection of Giant Cell Tumor of the Distal Radius – A Systematic Review and Meta-analysis

Article in several languages: português | English
Sheikh Muhammad Ebad Ali 
1   Departamento de Emergência, Mamji Hospital, Karachi, Paquistão
,
Syeda Safeena Fatima 
1   Departamento de Emergência, Mamji Hospital, Karachi, Paquistão
,
Bisma Munawar 
2   Karachi Medical and Dental College, Karachi, Paquistão
,
Maheen Fatima 
2   Karachi Medical and Dental College, Karachi, Paquistão
,
Syeda Kisa Batool Naqvi 
3   Dow University of Health Sciences, Karachi, Paquistão
,
Laiba Urooj Malik 
4   Shaheed Mohtarma Benazir Bhutto Medical College, Karachi, Paquistão
› Author Affiliations Financial Support The authors declare that the present study received no financial support from agencies in the public, private, or non-profit sectors.
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Abstract

Objective Surgical procedures of curettage and surgical resection are used to treat giant cell tumor (GCT) of the distal radius, but it is still controversial whether one provides better functional outcomes than the other. The present study aims to determine and compare both procedures regarding complications, local recurrence, and mobility.

Methods A complete search of the applicable literature was done and independently assessed by three authors. Included studies reported on patients who were surgically treated for GCT of the distal radius with either curettage or surgical resection. The Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) statement was used to obtain research regarding outcomes of surgical resection and curettage for GCT of the distal radius. A meta-analysis was performed using this data. Quality assessment was performed.

Results Seven studies, comprising 114 patients with resection and 108 with curettage, totaling 222 subjects with 117 males and 105 females, were included in the present review. Overall, patients in the curettage group had a higher recurrence rate (0.205; 95% confidence interval [95%CI] = 0.057–0.735; p = 0.015). Incidences in complications remains the same in both groups (2.845; 95%CI = 0.644–12.57; p = 0.168). Incidences in functional outcomes were the same in both groups as well (−0.948; 95%CI = −2.074–0.178; p = 0.099).

Conclusion The authors prefer resection and reconstruction for GCT of distal radius as optimum treatment method due to the similar functional outcomes and lower chances of recurrence. Curettage might be a treatment option in low-grade GCT coupled with adjuvant, neoadjuvant or ablation to reduce the risk of recurrence.

Keywords

curettage - fracture, distal radius - giant cell tumor of bone - margins of excision - operative surgical procedures

Work carried out at the Excemy Medical Research Community of Pakistan (EMRCP), Sindh, Karachi, Pakistan.




Publication History

Received: 05 December 2022

Accepted: 29 May 2023

Article published online:
21 December 2024

© 2024. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution 4.0 International License, permitting copying and reproduction so long as the original work is given appropriate credit (https://creativecommons.org/licenses/by/4.0/)

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