Subscribe to RSS
Download PDF
DOI: 10.1055/s-0044-1787824
Mucinous Cystic Neoplasm of the Liver: Case Report and Review of the Literature
Abstract
Mucinous cystic neoplasms of the liver (MCN-L) are a rare benign neoplasm of the biliary system that grows slowly with vague clinical symptoms. The malignant transformation in these tumors is high, and preoperative diagnosis using radiography or endoscopy is challenging. We present a case report of a 58-year-old female patient who presented with diffuse abdominal pain and nonprojectile vomiting. Abdominal ultrasound revealed characteristics that point to a hydatid cyst. The enhanced computed tomography revealed a well-defined multiloculated thin-walled fluid density lesion in the left lobe of the liver. After a left hemi-hepatectomy, a multiloculated cystic lesion in the liver with mucinous material as the content was discovered. Histopathology showed multiple cystic spaces were lined by mucin-secreting columnar epithelium without nuclear atypia, the wall of the cysts showed ovarian-like stroma, and the diagnosis of MCN-L was made. There was no recurrence after 6 months of regular follow-up.
Note
The manuscript has been read and approved by all the authors, that the requirements for authorship have been met, and each author believes that the manuscript represents honest work.
Publication History
Article published online:
18 June 2024
© 2024. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/)
Thieme Medical and Scientific Publishers Pvt. Ltd.
A-12, 2nd Floor, Sector 2, Noida-201301 UP, India
-
References
- 1 Nagtegaal ID, Odze RD, Klimstra D. et al; WHO Classification of Tumours Editorial Board. The 2019 WHO classification of tumours of the digestive system. Histopathology 2020; 76 (02) 182-188
- 2 Valasek MA, Yeh MM. Mucinous cystic neoplasm of the liver: clinicopathologic features and differential diagnosis. AJSP Rev Rep 2014; 19 (06) 293-296
- 3 Erdogan D, Lamers WH, Offerhaus GJ, Busch OR, Gouma DJ, van Gulik TM. Cystadenomas with ovarian stroma in liver and pancreas: an evolving concept. Dig Surg 2006; 23 (03) 186-191
- 4 Soni S, Pareek P, Narayan S, Varshney V. Mucinous cystic neoplasm of the liver (MCN-L): a rare presentation and review of the literature. Med Pharm Rep 2021; 94 (03) 366-371
- 5 Gao J, Zheng J, Cai J. et al. Differentiation and management of hepatobiliary mucinous cystic neoplasms: a single centre experience for 8 years. BMC Surg 2021; 21 (01) 146
- 6 Fragulidis GP, Pantiora EV, Kontis EA. et al. Biliary mucinous cystic neoplasm of the liver with ovarian stroma and elevated serum and cystic fluid cancer antigen 19–9 levels. Cureus 2017; 9 (11) e1863
- 7 Devaney K, Goodman ZD, Ishak KG. Hepatobiliary cystadenoma and cystadenocarcinoma. A light microscopic and immunohistochemical study of 70 patients. Am J Surg Pathol 1994; 18 (11) 1078-1091
- 8 Soochan D, Keough V, Wanless I, Molinari M. Intra and extra-hepatic cystadenoma of the biliary duct. Review of literature and radiological and pathological characteristics of a very rare case. BMJ Case Rep 2012; 2012: 0120125497