Abstract
Background Temporal lobe epilepsy (TLE) predisposes individuals to cognitive difficulties and
psychosocial consequences. Evaluating its impact on quality of life (QOL) is essential
for patient care.
Objective To identify factors influencing QOL in low-income patients with TLE.
Methods An institution-based cross-sectional study was conducted on 40 patients with TLE
during neurological consultations at a day clinic in Agadir, Morocco. The Quality
of Life in Epilepsy Inventory-31 (QOLIE-31) was used to measure QOL. Multivariate
linear regression analysis was performed to assess the associations between QOL and
demographic, clinical, psychiatric, social, and cognitive variables. Results were
considered statistically significant at a p-value < 0.05.
Results The mean overall QOL score was 48.14 ± 22.02. Among the seven scales of the QOLIE-31,
the Seizure Worry scale had the lowest mean score. Cognitive function, social support,
and self-esteem were positively associated with QOL. In contrast, memory complaints,
seizure duration, seizure frequency, anxiety, and depression were negatively associated
with QOL.
Conclusion While current interventions primarily target seizure control, our findings emphasize
the need for holistic approaches that address both cognitive and psychosocial challenges
to optimize QOL.
Keywords
Epilepsy, Temporal Lobe - Quality of Life - Cognition - Depression - Anxiety
Bibliographical Record
Amina Tani, Nawal Adali. Factors influencing quality of life in patients with temporal
lobe epilepsy. Arq Neuropsiquiatr 2025; 83: s00451802552.
DOI: 10.1055/s-0045-1802552
