Endoscopy, Table of Contents Endoscopy 2025; 57(S 02): S579DOI: 10.1055/s-0045-1806522 Abstracts | ESGE Days 2025 ePosters Endoscopic treatment of a large non-lifting lesion with advanced histology by hybrid EFTR: A case report Authors Author Affiliations M Sierra Morales 1 Hospital Universitario Príncipe de Asturias, Alcalá de Henares, Spain A Santos Rodriguez 1 Hospital Universitario Príncipe de Asturias, Alcalá de Henares, Spain P García Centeno 1 Hospital Universitario Príncipe de Asturias, Alcalá de Henares, Spain M Villafruela Cives 1 Hospital Universitario Príncipe de Asturias, Alcalá de Henares, Spain S Tabernero Da Veiga 1 Hospital Universitario Príncipe de Asturias, Alcalá de Henares, Spain Recommend Article Abstract Full Text References References 1 Mahadev S, Vareedayah AA, Yuen S. et al. Outcomes of a hybrid technique using EMR and endoscopic full-thickness resection for polyps not amenable to standard techniques (with video). Gastrointest Endosc 2021; 94: 358-67 2 Meier B, Elsayed I, Seitz N. et al. Efficacy and safety of combined EMR and endoscopic full-thickness resection (hybrid EFTR) for large nonlifting colorectal adenomas. Gastrointest Endosc 2023; 98: 405-11 3 Zwager LW, Mueller J, Stritzke B. et al. Adverse events of endoscopic full-thickness resection: results from the German and Dutch nationwide colorectal FTRD registry. Gastrointest Endosc 2023; 97: 780-9.e4