Abstract
Intraductal papillary mucinous neoplasms (IPMNs) are commonly identified cystic lesions
in the pancreas that may carry malignant potential for pancreatic ductal adenocarcinoma.
Risk stratification of identified lesions is critical to determine which patients
may benefit from surgical resection. Key high-risk features include size, growth,
main pancreatic duct involvement, obstructive jaundice, and enhancing solid components
on imaging. The surgical technique of choice depends on IPMN location, with pancreatoduodenectomy
being the most common procedure due to the high incidence of high-risk IPMNs in the
head of the pancreas. The extent of resection is guided by imaging and/or endoscopic
data, potentially including intraoperative frozen section analysis to assess for high-grade
dysplasia or invasive IPMN. Postoperative surveillance of the remnant gland is crucial
and based on the risk of disease recurrence after the surgery, which is determined
by the anatomopathological report.
Keywords
pancreatic cystic neoplasms - pancreatic cancer - intraductal papillary mucinous neoplasm
- pancreatic adenocarcinoma - pancreatic surgery
