Diabetologie und Stoffwechsel, Inhaltsverzeichnis Diabetologie und Stoffwechsel 2025; 20(S 01): S32-S33DOI: 10.1055/s-0045-1807416 Abstracts | DDG 2025 Poster Posterwalk 3: Grundlagenforschung Typ 2-Diabetes I Insulinresistenz Analysis of hippocampal miRNA expression changes and the effect of metformin treatment in diet-induced obese mice after 18 weeks Authors Institutsangaben M Gravel 1 Universität zu Lübeck, Institut für Humangenetik – AG Epigenetics and Metabolism, Lübeck, Germany C Krause 1 Universität zu Lübeck, Institut für Humangenetik – AG Epigenetics and Metabolism, Lübeck, Germany N Taege 2 Universität zu Lübeck, Institut für Experimentelle Endokrinologie, Lübeck, Germany H Kirchner 1 Universität zu Lübeck, Institut für Humangenetik – AG Epigenetics and Metabolism, Lübeck, Germany Artikel empfehlen Abstract Volltext Referenzen Literatur 1 Abdullah A.. et al. ‘The magnitude of association between overweight and obesity and the risk of diabetes: A meta-analysis of prospective cohort studies’. Diabetes Research and Clinical Practice 2010; 89 pp 309-319 2 Pedditizi E., Peters R., Beckett N.. ‘The risk of overweight/obesity in mid-life and late life for the development of dementia: a systematic review and meta-analysis of longitudinal studies’. Age and Ageing 2016; 45 pp 14-21 3 Talbot K.. et al. ‘Demonstrated brain insulin resistance in Alzheimer’s disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline’. The Journal of Clinical Investigation 2012; 122 pp 1316-1338 4 Campbell J.M.. et al. ‘Metformin Use Associated with Reduced Risk of Dementia in Patients with Diabetes: A Systematic Review and Meta-Analysis’. Journal of Alzheimer’s Disease 2018; 65 pp 1225-1236 5 Krause C.. et al. ‘Liver microRNA transcriptome reveals miR-182 as link between type 2 diabetes and fatty liver disease in obesity’, eLife. Edited by M.A. Mori and P.K. Mistry. 2024. 12. p RP92075
