Nuclear GSK3β/NFATc1 axis controls DNA repair mechanisms and drives therapy resistance in PDAC

M U Latif; G Schmidt; A Bockelmann; L Klein; S Mercan; K Reutlinger; L Huhnold; J Todorovic; P Ströbel; H Bastians; R Ashry; O H Krämer; S K Singh; V Ellenrieder

doi:10.1055/s-0045-1810962

Zeitschrift für Gastroenterologie, Table of Contents

Z Gastroenterol 2025; 63(08): e544
DOI: 10.1055/s-0045-1810962

Abstracts | DGVS/DGAV

Kurzvorträge

Innovative diagnostische & therapeutische Optionen bei pankreatikobiliären Karzinomen Donnerstag, 18. September 2025, 14:15 – 15:43, Seminarraum 6 + 7

Nuclear GSK3β/NFATc1 axis controls DNA repair mechanisms and drives therapy resistance in PDAC

Authors

M U Latif

¹University Medical Center Goettingen, Department of Gastroenterology, Gastrointestinal Oncology and Endocrinology, Goettingen, Deutschland
G Schmidt

¹University Medical Center Goettingen, Department of Gastroenterology, Gastrointestinal Oncology and Endocrinology, Goettingen, Deutschland
A Bockelmann

¹University Medical Center Goettingen, Department of Gastroenterology, Gastrointestinal Oncology and Endocrinology, Goettingen, Deutschland
L Klein

¹University Medical Center Goettingen, Department of Gastroenterology, Gastrointestinal Oncology and Endocrinology, Goettingen, Deutschland
S Mercan

¹University Medical Center Goettingen, Department of Gastroenterology, Gastrointestinal Oncology and Endocrinology, Goettingen, Deutschland
K Reutlinger

¹University Medical Center Goettingen, Department of Gastroenterology, Gastrointestinal Oncology and Endocrinology, Goettingen, Deutschland
L Huhnold

¹University Medical Center Goettingen, Department of Gastroenterology, Gastrointestinal Oncology and Endocrinology, Goettingen, Deutschland
J Todorovic

²University Medical Center Goettingen, Institute for Pathology, Goettingen, Deutschland
P Ströbel

²University Medical Center Goettingen, Institute for Pathology, Goettingen, Deutschland
H Bastians

³University Medical Center Goettingen, Department for Molecular Oncology, Goettingen, Deutschland
R Ashry

⁴University Medical Center, Department of Toxicology, Mainz, Deutschland
O H Krämer

⁴University Medical Center, Department of Toxicology, Mainz, Deutschland
S K Singh

¹University Medical Center Goettingen, Department of Gastroenterology, Gastrointestinal Oncology and Endocrinology, Goettingen, Deutschland
V Ellenrieder

¹University Medical Center Goettingen, Department of Gastroenterology, Gastrointestinal Oncology and Endocrinology, Goettingen, Deutschland