Abstract
Neurogenic shock is thus defined as autonomic failure, leading to hypotension, bradycardia,
and metabolic vasodilation. The primary pathology lies in the cessation of the sympathetic
outflow following the spinal or brain stem injury insult. Thus, an understanding of
the neuroanatomic substrate of neurogenic shock's pathophysiology is a prerequisite
for a successful approach to diagnosis and therapy. Therefore, this narrative review
will comprehensively discuss the neuroanatomic structures involved in the pathology
of neurogenic shock, emphasizing their functional significance in the context of the
impairment consequences.
Keywords
neurogenic shock - autonomic failure - hypotension - bradycardia - sympathetic outflow
- spinal cord injury - pathophysiology - autonomic nervous system