CLOVES Syndrome: An Unusual Cause of Vascular Malformations and Soft Tissue Overgrowth

Abstract

CLOVES syndrome is a rare congenital disorder characterized by Congenital Lipomatous Overgrowth of the trunk and/or thorax, Vascular malformations, skin abnormalities (such as linear Epidermal nevi), and Skeletal anomalies, with scoliosis and tethered cord being common features. This report presents the case of a 17-year-old boy with clinical and imaging features consistent with CLOVES syndrome, confirmed by genetic analysis demonstrating a somatic PIK3CA mutation.

Keywords

CLOVES - soft tissue overgrowth - vascular malformations

• References

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