Synthesis 1990; 1990(1): 41-43
DOI: 10.1055/s-1990-26782
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Synthesis of Diethyl (1-Aminoalkyl)phosphonates Under Solid-Liquid Phase-Transfer Catalysis Conditions

J. P. Genet* , J. Uziel, A. M. Touzin, S. Juge
  • *Laboratoire de Synthèse Organique, Associé au CNRS, Ecole Nationale Supérieure de Chimie de Paris, 11, rue P et M. Curie, F-75231 Paris, France
Weitere Informationen


17. September 2002 (online)

Alkylations of the stable diethyl N-(diphenylmethylene) aminomethylphosphonate (1) under solid-liquid phase-transfer catalysis (PTC) with or without solvent to give N-(diphenylmethylene) aminomethylphosphonic esters 2 are described. Acidic hydrolysis of 2 afforded diethyl (1-aminoalkyl)phosphonates 3 in good yields.