Synthesis 1990; 1990(1): 53-56
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Efficient Preparation of Optically Pure Wieland-Miescher Ketone and Confirmation of Its Absolute Stereochemistry by the CD Exciton Chirality Method

Nobuyuki Harada* , Tatsuo Sugioka, Hisashi Uda, Takeo Kuriki
  • *Chemical Research Institute of Nonaqueous Solutions, Tohoku University, 2-1-1 Katahira, Sendai 980, Japan
Further Information

Publication History

Publication Date:
17 September 2002 (online)

An efficient preparation procedure of optically pure Wieland-Miescher ketone, (8aR)-(-)-3,4,8,8a-tetrahydro-8a-methyl-1,6(2H, 7H)-naphthalenedione (1), is described, and its absolute stereochemistry is confirmed by the application of the CD exciton chirality method to its derivatives.