Synthesis and Dehydrobromination of α-Bromo Aldehyde and Ketone Nitroxyl Radical Spin Labels
17. September 2002 (online)
Various types of α-bromo aldehyde and ketone derivatives of nitroxyl radicals can be prepared in a selective bromination reaction with pyrrolidone hydrotribromide in the presence of a double bond. The saturated α-bromo aldehydes are dehydrobrominated with 1,8-diazabicyclo [5,4,0]undec-7-ene.