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Synthesis 1990; 1990(2): 119-122
DOI: 10.1055/s-1990-26804
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Convenient Syntheses of Fluorenylmethyl-Based Side Chain Derivatives of Glutamic and Aspartic acids, Lysine, and Cysteine

F. Albericio* , E. Nicolás, J. Rizo, M. Ruiz-Gayo, E. Pedroso, E. Giralt
  • *Department de Química Orgànica, Facultat de Química, Universitat de Barcelona, E-08028 Barcelona, Spain
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Publication Date:
17 September 2002 (online)

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Efficient and practical one-pot syntheses of the fluorenylmethyl-based side chain derivatives of glutamic and aspartic acids, lysine, and cysteine are described. Likewise, stability/lability of these derivatives towards solvents and reagents used in solid phase peptide synthesis are discussed.

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