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Synthesis 1990; 1990(2): 156-159
DOI: 10.1055/s-1990-26820
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The Synthesis of Triazole Analogues of Antitumor Dehydropyrrolizidine Alkaloids

William H. Pearson* , Stephen C. Bergmeier, Jayne A. Chytra
  • *Department of Chemistry and Department of Medicinal Chemistry, University of Michigan, Ann Arbor, Michigan, MI 4809, USA
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Publication Date:
17 September 2002 (online)

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Several mono- and disubstituted 5,6-dihydro-4H-pyrrolo[1,2-c] [1,2,3]triazoles have been prepared via intramolecular 1,3-dipolar cycloadditions of azides with alkynes. These triazoles are analogues of the antitumor dehydropyrrolizidine alkaloids.

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