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Synthesis 1990; 1990(3): 214-215
DOI: 10.1055/s-1990-26834
DOI: 10.1055/s-1990-26834
paper
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A Convenient Synthesis of Isothiazolo[5,4-b]indole (Brassilexin) via a Polyphosphoric Acid Initiated Ring Closure
Further Information
Publication History
Publication Date:
17 September 2002 (online)
Brassilexin (4), an antifungal compound previously isolated from Brassica juncea L. (Cruciferae), has been synthesized with an overall yield of 11% starting from 3-indolecarbaldehyde (1).