Synthesis 1990; 1990(6): 491-492
DOI: 10.1055/s-1990-26915
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

A Convenient Synthesis of 3-Alkyl-6-trifluoromethyl-3,6-dihydro-2H-1,3,4-thiadiazines

Yasuhiro Kamitori* , Masaru Hojo, Ryōichi Masuda, Yoshihiko Kawamura, Tōru Numai
  • *Department of Industrial Chemistry, Faculty of Engineering, Kobe University, Kobe 657, Japan
Weitere Informationen


17. September 2002 (online)

3-Dialkylhydrazono-1,1,1-trifluoro-2-alkanones 2, readily obtainable from the reaction of substituted benzaldehyde, propanal and formaldehyde dialkylhydrazones with trifluoroacetic anhydride, afford title compounds 5 in satisfactory yields on treatment with Lawesson reagent in refluxing benzene.