Synthesis 1990; 1990(12): 1133-1134
DOI: 10.1055/s-1990-27113
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A New and Concise Synthesis of 3-Aryl- and 3-Alkyl-1H-2-benzothiopyran-1-ones (Thioisocoumarins)

Axel Couture* , Hélène Cornet, Pierre Grandclaudon
  • *Laboratoire de Chimie Organique Physique, U.R.A. C.N.R.S. No 351, Université des Sciences et Techniques de Lille Flandres-Artois, F-59655 Villeneuve d'Ascq Cédex, France
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Publication History

Publication Date:
02 May 2002 (online)

3-Aryl- and 3-alkyl-1H-2-benzothiopyran-1-ones are readily accessible by reaction of the lithiated N,N-diethyl-o-toluamide (N,N-diethyl-2-methylbenzenecarboxamide) with appropriate aromatic, heteroaromatic and aliphatic thioesters.

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