Concave Reagents 13. 2′-Substituted m-Terphenyls as Building Blocks. Synthesis of a Concave Thiol Acetate
19. März 2002 (online)
New sterically highly hindered 2′-substituted 2,2″, 6,6″-tetramethyl-m-terphenyls 1 were synthesized. Lithiation of the 2′-iodide 1b and subsequent reaction with electrophiles gave new m-terphenyls 1f - 1j, group transformations gave 1k - 1p. The thiol acetate 1o could be tetra-functionalized and doubly bridged to form a bimacrocyclic concave thiol acetate 3.