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Synlett 1996; 1996(2): 141-142
DOI: 10.1055/s-1996-5358
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Synthesis of (±)-Crotomachlin

Toshiyuki Teramoto, Takeo Yuno, Hajime Morita, Shigeo Katsumura, Kazuhiko Sakaguchi* , Sachihiko Isoe1
  • *Department of Material Science, Faculty of Science, Osaka City University, Sugimoto 3-3-138, Sumiyoshi, Osaka 558, Japan, Fax 06 605 2570; E-mail h1628@ocugw.cc.osaka-cu.ac.jp
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Publication History

Publication Date:
31 December 2000 (online)

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An efficient synthesis of (±)-crotomachlin (1) was accomplished starting from 4,4,10-trimethyl-9-methylene-Δ6-8-octalone (4) in 7 steps.

crotomachlin - diterpene - antilipoxygenase activity - 3-methylsulfolene - pyrolysis

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