Synlett 1996; 1996(5): 473-474
DOI: 10.1055/s-1996-5445
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Palladium(0) Catalyzed Cross Coupling Reactions of Hindered, Double Activated Aryl Halides with Organozinc Reagents - The Effect of Copper(I) Cocatalysis

Andreas Weichert* , Martina Bauer, Petra Wirsig
  • *HOECHST AG, Pharma Research, TD Cardiovascular Agents, G 838, 65926 Frankfurt/Germany
Further Information

Publication History

Publication Date:
31 December 2000 (online)

Various organozinc reagents undergo palladium(0) catalyzed Negishi-Kumada-type cross coupling reactions, cocatalyzed by copper(I) iodide, with electronically activated aryl halides 1-d in the presence of an electron withdrawing ortho or meta substituent and an ester group.