Synthesis of Phosphotriester Cationic Phospholipids. Cationic Lipids 21
31 December 2000 (online)
The synthesis of cationic phospholipids (CP) by neutralization of the negative charge of the phosphodiester moiety is described. It involves esterification of the remaining P-O- linkage of the phospholipid by reaction with substituted sulfochlorides in the presence of C1-C4 alcohols.
cationic lipids - phospholipids - cationic liposomes - gene transfection - drug delivery