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Synlett 1996; 1996(10): 983-984
DOI: 10.1055/s-1996-5647
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Enantioselective Synthesis of Cyclic Ethers via Hetero Diels-Alder Reaction. Formal Synthesis of (+)- and (-)-Laurecin

M. Teresa Mujica, María M. Afonso, Antonio Galindo, J. Antonio Palenzuela*
  • *Instituto Universitario de Bio-Orgánica ”Antonio González”, Universidad de La Laguna, 38206 La Laguna, Tenerife, Spain, Fax +34 (22) 630095, e-mail jpalenzuela@ull.es
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Publication Date:
31 December 2000 (online)

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A formal synthesis of (+)- and (-)-laurecin has been accomplished, using a hetero Diels-Alder reaction between a monoactivated diene and (S)-(-)-2,3-O-isopropylidene-gylceraldehyde or its enantiomer as the key step.

(+) Laurencin - cyclic ethers - enantioselective synthesis - hetero Diels-Alder reaction

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